Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | UBE2D3 | P61077 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10261465 | 0.90 | MAPK1 (0.39) | MAPK1KMT2AMGLLGRM5SLC6A2 | |
| SCHEMBL14860981 | 0.89 | MAPK1 (0.48) | MAPK1KMT2AMGLLALDH1A1CYP1A2 | |
| SCHEMBL22076666 | 0.83 | MGLL (0.33) | MAPK1KMT2AMGLL | |
| SCHEMBL4897945 | 0.83 | CA12 (0.46) | MAPK1KMT2AMGLLALDH1A1 | |
| SCHEMBL15305953 | 0.81 | MAPK1 (0.43) | MAPK1KMT2AMGLLALDH1A1CYP1A2 | |
| SCHEMBL317700 | 0.81 | PLA2G7 (0.50) | MAPK1KMT2AHDAC1ALDH1A1HPGD | |
| SCHEMBL1284517 | 0.81 | TSHR (0.48) | MAPK1KMT2AALDH1A1 | |
| SCHEMBL13950373 | 0.81 | MAPK1 (0.43) | MAPK1KMT2AMGLLALDH1A1CYP1A2 | |
| SCHEMBL11595533 | 0.81 | MAPK1 (0.43) | MAPK1KMT2AMGLLALDH1A1CYP1A2 | |
| SCHEMBL1696190 | 0.81 | NPC1 (0.47) | MAPK1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025046227-A1 | X-RAY VISIBLE IMPLANTABLE SCAFFOLDS | UCL BUSINESS LTD (GB) | 2025-03-06 | — | — | WO | claimed |
| WO-2025046227-A1 | X-RAY VISIBLE IMPLANTABLE SCAFFOLDS | UCL BUSINESS LTD (GB) | 2025-03-06 | — | — | WO | disclosed |
| US-12023389-B2 | Compositions that target tumor-associated macrophages and methods of use therefor | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-07-02 | — | — | US | disclosed |
| EP-4379725-A2 | IMMUNE RECOGNITION MOTIFS | Iogenetics, LLC. (US) | 2024-06-05 | — | — | EP | disclosed |
| US-20240131201-A1 | COMPOSITIONS THAT TARGET TUMOR-ASSOCIATED MACROPHAGES AND METHODS OF USE THEREFOR | Sanford Burnham Prebys Medical Discovery Institute | 2024-04-25 | — | — | US | disclosed |
| WO-2024023332-A1 | SILICON-BASED FLUORIDE ACCEPTOR GROUPS FOR RADIOPHARMACEUTICALS | Technische Universität München (DE) | 2024-02-01 | — | — | WO | disclosed |
| EP-3167396-B1 | IMMUNE RECOGNITION MOTIFS | IOGENETICS LLC (US) | 2024-01-17 | — | — | EP | disclosed |
| EP-4185336-A1 | SILICON-CONTAINING LIGAND COMPOUNDS | Technische Universität München (DE) | 2023-05-31 | — | — | EP | disclosed |
| US-11571484-B2 | Compositions that target tumor-associated macrophages and methods of use therefor | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-02-07 | — | — | US | disclosed |
| US-20220348681-A1 | FUSED PROTEIN OF AN ANTIBODY WHICH RECOGNIZES CANCER-CELLS AND A STREPTAVIDIN MUTANT | THE UNIVERSITY OF TOKYO (JP) | 2022-11-03 | — | — | US | disclosed |
| WO-2009138763-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009138763-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2009-11-19 | — | — | WO | disclosed |
| US-20090286992-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2009-11-19 | — | — | US | disclosed |
| US-20090005545-A1 | METHODS FOR PURIFYING RADIOLABELLED COMPOUNDS | MCMASTER UNIVERSITY | 2009-01-01 | — | — | US | disclosed |
| US-7335347-B2 | Methods for purifying radiolabelled compounds | MCMASTER UNIVERSITY (CA) | 2008-02-26 | — | — | US | disclosed |
| EP-1135170-B1 | RADIOCONJUGATION OF INTERNALIZING ANTIBODIES | UNIV DUKE (US) | 2006-10-25 | — | — | EP | disclosed |
| US-6998106-B1 | Radioconjugation of internalizing antibodies | DUKE UNIVERSITY (US) | 2006-02-14 | — | — | US | disclosed |
| US-6426400-B1 | COMPLEXES | DUKE UNIVERSITY | 2002-07-30 | — | — | US | disclosed |
| EP-1135170-A2 | RADIOCONJUGATION OF INTERNALIZING ANTIBODIES | DUKE UNIVERSITY (US) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000032240-A2 | RADIOCONJUGATION OF INTERNALIZING ANTIBODIES | DUKE UNIVERSITY (US) | 2000-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286992-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | RARB, RARG, RARA | MAPK1 1701/4885KMT2A 1417/4885MGLL 4447/4885 |
| US-20220348681-A1 | FUSED PROTEIN OF AN ANTIBODY WHICH RECOGNIZES CANCER-CELLS AND A STREPTAVIDIN MUTANT | SPEN, IGSF11, MYCBP | MAPK1 3555/4885KMT2A 1440/4885MGLL 4746/4885 |
| US-20090005545-A1 | METHODS FOR PURIFYING RADIOLABELLED COMPOUNDS | PAICS, PFAS, NPEPPS | MAPK1 4277/4885KMT2A 2099/4885MGLL 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.