Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3183675 | 0.78 | SIGMAR1 (0.44) | ALDH1A1CYP1A2CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL10408259 | 0.78 | GABRA1 (0.42) | GABRA1GABRB1LPAR1MAPK1ALDH1A1 | |
| SCHEMBL2100737 | 0.76 | STAT3 (0.40) | GABRA1GABRB1LPAR1MAPK1ALDH1A1 | |
| SCHEMBL3181155 | 0.74 | ALDH1A1 (0.45) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3185380 | 0.74 | NPC1 (0.42) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3168174 | 0.74 | MAPK1 (0.42) | GABRA1MAPK1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3182842 | 0.74 | LPAR1 (0.45) | LPAR1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3182943 | 0.74 | L3MBTL1 (0.50) | GABRA1GABRB1HSP90AA1HSP90AB1CYP1A2 | |
| SCHEMBL29542895 | 0.73 | ALDH1A1 (0.55) | GABRA1GABRB1LPAR1MAPK1ALDH1A1 | |
| SCHEMBL2737246 | 0.73 | L3MBTL1 (0.59) | GABRA1GABRB1LPAR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652062-B2 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | WYETH LLC (US) | 2010-01-26 | — | — | US | disclosed |
| EP-1910284-A1 | CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | Wyeth (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20080064673-A1 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | WYETH (US) | 2008-03-13 | — | — | US | disclosed |
| US-7297713-B2 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | WYETH (US) | 2007-11-20 | — | — | US | disclosed |
| WO-2007016211-A1 | CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |
| US-20070027125-A1 | Cyanopyrrole-phenyl progesterone receptor modulators and uses thereof | WYETH (US) | 2007-02-01 | — | — | US | disclosed |
| US-20070027201-A1 | Use of progesterone receptor modulators | WYETH (US) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064673-A1 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | PGR, GNRHR, PGRMC1 | GABRA1 447/4885GABRB1 570/4885HSP90AA1 2372/4885 |
| US-20070027125-A1 | Cyanopyrrole-phenyl progesterone receptor modulators and uses thereof | PGR, PGRMC1, PGRMC2 | GABRA1 388/4885GABRB1 467/4885HSP90AA1 2711/4885 |
| US-20070027201-A1 | Use of progesterone receptor modulators | GNRHR, PGR, FSHR | GABRA1 558/4885GABRB1 511/4885HSP90AA1 3262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.