SCHEMBL3192410

SCHEMBL3192410

O=C1C=Cc2c1ccc1c2ccc2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.69
CYP1A2 P05177 2/20 0.69
CYP2C9 P11712 2/20 0.69
CYP2C19 P33261 2/20 0.69
HIF1A Q16665 2/20 0.69
MEN1 O00255 1/20 0.69
USP2 O75604 1/20 0.69
LMNA P02545 1/20 0.69
TP53 P04637 1/20 0.69
CYP2D6 P10635 1/20 0.69
HPGD P15428 1/20 0.69
ALOX12 P18054 1/20 0.69
MAPK1 P28482 1/20 0.69
KMT2A Q03164 1/20 0.69
HPRT1 P00492 3/20 0.52
PAX8 Q06710 1/20 0.48
CES1 P23141 1/20 0.47
CDC25A P30304 2/20 0.47
CDC25C P30307 2/20 0.47
ARSA P15289 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4826194 0.91 ALDH1A1 (0.62) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL8641042 0.90 ALDH1A1 (0.59) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL28569069 0.85 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL15235 0.83 CES1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL29384620 0.83 CES1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A
Methane SCHEMBL25275368 0.81 CES1 (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL893374 0.81 ALDH1A1 (1.00) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A
Lithium SCHEMBL30194812 0.81 CES1 (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A
Water SCHEMBL8525158 0.81 CES1 (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A
SCHEMBL30702421 0.81 ALDH1A1 (1.00) ALDH1A1CYP1A2CYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367649-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2025-12-04 US disclosed
CN-118206604-A Synthesis method of monovalent gold catalyzed 1, 3-diene-1-carbonyl derivative 沈阳药科大学 2024-06-18 CN disclosed
US-20240139205-A1 MODULATORS OF ARALAR FOR TREATING NEUROLOGICAL DISORDERS UNIVERSITE DE LAUSANNE (CH) 2024-05-02 US disclosed
CN-112125891-B N2Selective tetrahydrofuran/tetrahydrothiophene substituted triazole derivative and synthesis method and application thereof 华东师范大学 2022-06-07 CN disclosed
CN-112125891-A N2Selective tetrahydrofuran/tetrahydrothiophene substituted triazole derivative and synthesis method and application thereof 华东师范大学 2020-12-25 CN disclosed
WO-2019154257-A1 STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF 江苏豪森药业集团有限公司 2019-08-15 WO disclosed
US-9779901-B2 High temperature material compositions for high temperature thermal cutoff devices THERM-O-DISC, INCORPORATED (US) 2017-10-03 US disclosed
US-20150162153-A1 HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES THERM-O-DISC, INCORPORATED (US) 2015-06-11 US disclosed
US-8961832-B2 High temperature material compositions for high temperature thermal cutoff devices THERM-O-DISC, INCORPORATED (US) 2015-02-24 US disclosed
US-20120121795-A1 HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES THERM-O-DISC, INCORPORATED (US) 2012-05-17 US disclosed
US-20100033295-A1 HIGH TEMPERATURE THERMAL CUTOFF DEVICE THERM-O-DISC, INCORPORATED (US) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120121795-A1 HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES HTT, HTR1A, TPH1 ALDH1A1 410/4885CYP1A2 1944/4885CYP2C9 1341/4885
US-20250367649-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF PPOX, AOX1, CYP3A7 ALDH1A1 199/4885CYP1A2 11/4885CYP2C9 9/4885
US-20240139205-A1 MODULATORS OF ARALAR FOR TREATING NEUROLOGICAL DISORDERS CYFIP1, GABARAPL1, GABRR1 ALDH1A1 1024/4885CYP1A2 2311/4885CYP2C9 4165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.