SCHEMBL3194752

SCHEMBL3194752

Cc1cccc(C(=O)NC(C)C)c1N

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.49
CHRM2 P08172 2/20 0.46
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTT P42858 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5584122 0.83 ALDH1A1 (0.43) CHRM2ALDH1A1KDM4ESMN1; SMN2CYP2D6
SCHEMBL27744255 0.83 ALDH1A1 (0.39) CHRM2ALDH1A1KDM4ESMN1; SMN2LMNA
SCHEMBL25607328 0.82 NPC1 (0.51) ALOX5ALDH1A1PKMCYP1A2CYP2D6
SCHEMBL394511 0.82 HPGD (0.56) ALDH1A1KDM4EL3MBTL1PKMSMN1; SMN2
SCHEMBL21612254 0.82 ALDH1A1 (0.38) CHRM2ALDH1A1KDM4ESMN1; SMN2CYP2D6
SCHEMBL10101480 0.82 CNR1 (0.41) CHRM2ALDH1A1KDM4ESMN1; SMN2
SCHEMBL15228675 0.81 ALDH1A1 (0.48) ALOX5ALDH1A1KDM4EL3MBTL1PKM
SCHEMBL28023692 0.81 PTGS2 (0.46) ALDH1A1KDM4ESMN1; SMN2CYP2D6CYP2C19
SCHEMBL635088 0.80 PLK1 (0.50) ALDH1A1KDM4ESMN1; SMN2HTTLMNA
SCHEMBL31038153 0.80 PLK1 (0.50) ALDH1A1KDM4ESMN1; SMN2HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106336395-A Benzamide derivatives containing urea bridge and preparation method and application thereof 浙江工业大学 2017-01-18 CN disclosed
CN-106236751-A The application in preparing cancer therapy drug of a kind of benzamide derivatives containing urea bridge 浙江工业大学 2016-12-21 CN disclosed
US-9173400-B2 Anthranilamide arthropodicide treatment E I DU PONT DE NEMOURS AND COMPANY (US) 2015-11-03 US disclosed
US-9113630-B2 Method of controlling particular insect pests by applying anthranilamide compounds E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-25 US disclosed
US-20140141972-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E I DU PONT NEMOURS AND COMPANY (US) 2014-05-22 US disclosed
US-20140140973-A1 METHOD OF CONTROLLING PARTICULAR INSECT PESTS BY APPLYNG ANTHRANILAMIDE COMPOUNDS E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-22 US disclosed
US-8697734-B2 Method for controlling particular insect pests by applying anthranilamide compounds E I DU PONT DE NEMOURS AND COMPANY (US) 2014-04-15 US disclosed
US-8637552-B2 Anthranilamide arthropodicide treatment E I DU PONT DE NEMOURS AND COMPANY (US) 2014-01-28 US disclosed
EP-1467988-B1 Quinazoline(di)ones for invertebrate pest control DU PONT (US) 2013-07-17 EP disclosed
US-20130031677-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-31 US disclosed
EP-1423379-A1 ORTHO-SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS E.I. du Pont de Nemours and Company (US) 2004-06-02 EP disclosed
EP-1416796-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
US-20030229050-A1 Insecticidal anthranilamides FMC CORPORATION 2003-12-11 US disclosed
WO-2003062226-A1 QUINAZOLINE(DI) ONES FOR INVERTEBRATE PEST CONTROL E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-07-31 WO disclosed
CN-1419537-A Insecticidal anthranilamides DU PONT (US) 2003-05-21 CN disclosed
WO-2003024222-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-03-27 WO disclosed
WO-2003016300-A1 ORTHO-SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed
WO-2003015518-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed
EP-1265850-A2 INSECTICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-12-18 EP disclosed
WO-2001070671-A2 INSECTICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140140973-A1 METHOD OF CONTROLLING PARTICULAR INSECT PESTS BY APPLYNG ANTHRANILAMIDE COMPOUNDS ANTXR2, NIT2, TDO2 ALOX5 103/4885CHRM2 348/4885ALDH1A1 2266/4885
US-20130031677-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT ANTXR2, ARF5, NPR1 ALOX5 255/4885CHRM2 493/4885ALDH1A1 933/4885
US-20030229050-A1 Insecticidal anthranilamides ANTXR2, NIT2, CYB5R3 ALOX5 1065/4885CHRM2 824/4885ALDH1A1 949/4885
US-20140141972-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT ANTXR2, ARF5, NPR1 ALOX5 255/4885CHRM2 493/4885ALDH1A1 933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.