SCHEMBL3194800

SCHEMBL3194800

O=C(c1cc(C(=O)O)c(C(=O)O)c(C(F)(F)F)c1)c1cc(C(=O)O)c(C(=O)O)c(C(F)(F)F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ASPH Q12797 1/20 0.42
▸ SRD5A2 P31213 4/20 0.39
▸ AKR1C3 P42330 3/20 0.38
▸ AKR1C2 P52895 2/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ CDC25A P30304 1/20 0.38
▸ CDC25B P30305 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ TAS2R14 Q9NYV8 1/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ NOTUM Q6P988 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ CES2 O00748 2/20 0.34
▸ VNN1 O95497 1/20 0.34
▸ CNR1 P21554 1/20 0.33
▸ CNR2 P34972 1/20 0.33
▸ CFTR P13569 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404413 0.81 ASPH (0.44) ASPHAKR1C2HSD17B10TAS2R14KDM4E
SCHEMBL1098875 0.81 ASPH (0.44) ASPHAKR1C2HSD17B10TAS2R14KDM4E
Water SCHEMBL25435119 0.79 ASPH (0.43) ASPHAKR1C2HSD17B10TAS2R14KDM4E
SCHEMBL8037311 0.79 CES2 (0.47) ASPHAKR1C3AKR1C2HSD17B10TAS2R14
SCHEMBL1635186 0.79 ASPH (0.46) ASPHAKR1C3AKR1C2HSD17B10TAS2R14
SCHEMBL28053969 0.78 RXRA (0.41) ASPHSRD5A2HSD17B10POLBTDP1
SCHEMBL3176700 0.76 ASPH (0.41) ASPHAKR1C3AKR1C2HSD17B10POLB
SCHEMBL8037245 0.75 ASPH (0.40) ASPHSRD5A2HSD17B10TAS2R14KDM4E
SCHEMBL9156778 0.73 ASPH (0.38) ASPHAKR1C2HSD17B10KDM4ENOTUM
SCHEMBL9152486 0.73 POLB (0.42) ASPHAKR1C3AKR1C2HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 — — EP claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 — — US claimed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 — — EP claimed
US-20240352194-A1 POLYIMIDE FOR SPACECRAFT, POLYIMIDE FILM FOR SPACECRAFT, AND SPACECRAFT MEMBER INCLUDING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-10-24 — — US disclosed
EP-4446360-A1 POLYIMIDE FOR SPACECRAFT, POLYIMIDE FILM FOR SPACECRAFT, AND SPACECRAFT MEMBER INCLUDING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-10-16 — — EP disclosed
WO-2024071066-A1 METAL-CLAD LAMINATED PLATE 日鉄ケミカル&マテリアル株式会社 2024-04-04 — — WO disclosed
WO-2023189319-A1 AMINO COMPOUND, POLYAMIDE ACID AND POLYIMIDE USING SAID AMINO COMPOUND, AND METHOD FOR PRODUCING SAME 日鉄ケミカル&マテリアル株式会社 2023-10-05 — — WO disclosed
WO-2023106369-A1 POLYIMIDE FOR SPACECRAFT, POLYIMIDE FILM FOR SPACECRAFT, AND SPACECRAFT MEMBER INCLUDING SAME 日鉄ケミカル&マテリアル株式会社 2023-06-15 — — WO disclosed
WO-2022230546-A1 POROUS POLYIMIDE FILM 東京応化工業株式会社 2022-11-03 — — WO disclosed
US-20210340325-A1 POLYIMIDE PRECURSOR, POLYIMIDE PRODUCED FROM SAME, AND FLEXIBLE DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-11-04 — — US disclosed
US-10696845-B2 Energy-sensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 2020-06-30 — — US disclosed
US-5316805-A Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1994-05-31 — — US disclosed
US-5262277-A Light sensitive elements for electrical thick films with heat resistance HITACHI CHEMICAL COMPANY, INC. (JP) 1993-11-16 — — US disclosed
EP-0219336-B1 LIQUID CRYSTAL ORIENTATION CONTROLLING FILM AND LIQUID CRYSTAL DEVICE USING THE SAME Hitachi Chemical Co., Ltd. (JP) 1993-07-21 — — EP disclosed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 — — US disclosed
US-5108201-A From 3,3'-diamino-2,2'-bis(trifluoromethyl)biphenyl monomer NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-28 — — US disclosed
EP-0454590-A2 Polyimide optical waveguide NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-10-30 — — EP disclosed
EP-0373952-A2 Photosensitive resin composition and photosensitive element using the same Hitachi Chemical Co., Ltd. (JP) 1990-06-20 — — EP disclosed
US-4735492-A POLYIMIDE-ISOIDOLOQUINAZOLINEDIONE HITACHI CHEMICAL COMPANY, LTD. (JP) 1988-04-05 — — US disclosed
EP-0219336-A2 Liquid crystal orientation controlling film and liquid crystal device using the same Hitachi Chemical Co., Ltd. (JP) 1987-04-22 — — EP disclosed
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