SCHEMBL319642

SCHEMBL319642

CCO[Si](CCCCl)(OCC)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.34
LTA4H P09960 2/20 0.32
SLC9A1 P19634 1/20 0.30
RELA Q04206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647736 0.89 TSHR (0.33) LTA4H
SCHEMBL707984 0.89 LTA4H (0.32) LTA4H
SCHEMBL703455 0.85 LTA4H (0.36) SMN1; SMN2LTA4HSLC9A1
SCHEMBL645725 0.85 LTA4H (0.34) SMN1; SMN2LTA4HRELA
SCHEMBL7764812 0.84 ALDH1A1 (0.33)
SCHEMBL19470825 0.84 LTA4H (0.37) SMN1; SMN2LTA4HSLC9A1
SCHEMBL1069349 0.82 MAOA (0.34)
SCHEMBL19470880 0.82 KCNH2 (0.39) SMN1; SMN2LTA4HSLC9A1
SCHEMBL28537234 0.82 NR1H2 (0.32) LTA4H
SCHEMBL19470850 0.82 KCNH2 (0.39) SMN1; SMN2LTA4HSLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10221200-B2 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2019-03-05 US disclosed
US-9796738-B2 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2017-10-24 US disclosed
US-20170233416-A1 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2017-08-17 US disclosed
EP-2590988-B1 QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE EVONIK DEGUSSA GMBH (DE) 2017-03-01 EP disclosed
CN-103080117-B Season amino alcohol official can organo-silicon compound, compositions containing this compound and their preparation and purposes 赢创德固赛有限公司 2016-08-03 CN disclosed
CN-102405224-B Comprise composition and the Synthesis and applications thereof of season amino-functional silicoorganic compound EVONIK DEGUSSA GMBH (DE) 2015-12-16 CN disclosed
EP-2421874-B1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2015-09-30 EP disclosed
US-9120900-B2 Polymer-bound bisacylphosphine oxides BASF SE (DE) 2015-09-01 US disclosed
US-8979996-B2 Composition containing quaternary amino-functional organosilicon compunds and production and use thereof EVONIK DEGUSSA GMBH (DE) 2015-03-17 US disclosed
US-8980960-B2 Methods for producing a dispersion containing silicon dioxide particles and cationization agent EVONIK DEGUSSA GMBH (DE) 2015-03-17 US disclosed
WO-2012004044-A1 METHODS FOR PRODUCING A DISPERSION CONTAINING SILICON DIOXIDE PARTICLES AND CATIONIZATION AGENT EVONIK DEGUSSA GMBH (DE) 2012-01-12 WO disclosed
WO-2012004082-A2 QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE EVONIK DEGUSSA GMBH (DE) 2012-01-12 WO disclosed
US-20120006228-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2012-01-12 US disclosed
WO-2011003772-A1 POLYMER-BOUND BISACYLPHOSPHINE OXIDES BASF SE (DE) 2011-01-13 WO disclosed
WO-2010121878-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2010-10-28 WO disclosed
WO-2010121873-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2010-10-28 WO disclosed
US-4524169-A THERMOPLASTIC RUBBER, SILICATE FILLER, AND AN ORGANOSILICON COMPOUND DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-06-18 US disclosed
US-4390712-A Aqueous solution of cationic organosilicon compounds and process for the production of the solutions DEGUSSA AG (DE) 1983-06-28 US disclosed
US-4297145-A HALOALKYL MONO-, DI-, OR TRIORGANO SILANES WITH CARBON BLACK OR SILICA FOR MOLDING NATURAL OR SYNTHETIC RUBBERS DEGUSSA AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
US-4222915-A Vulcanizable halorubber mixtures DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-09-16 US disclosed