Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 10/20 | 0.45 |
| ▸ | RARB | P10826 | 9/20 | 0.45 |
| ▸ | RARA | P10276 | 8/20 | 0.45 |
| ▸ | RXRA | P19793 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319810 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TDP1POLBGLAL3MBTL1 | |
| SCHEMBL5830531 | 0.88 | AKR1C3 (0.52) | ALDH1A1TDP1POLBGLAL3MBTL1 | |
| SCHEMBL5830527 | 0.88 | AKR1C3 (0.52) | ALDH1A1TDP1POLBGLAL3MBTL1 | |
| SCHEMBL8136582 | 0.86 | NOS3 (0.47) | ALDH1A1TDP1POLBGLAL3MBTL1 | |
| SCHEMBL7800031 | 0.86 | NOS3 (0.47) | ALDH1A1TDP1POLBGLAL3MBTL1 | |
| SCHEMBL3218915 | 0.84 | AKR1C3 (0.67) | ALDH1A1TDP1POLBGLAL3MBTL1 | |
| SCHEMBL554744 | 0.82 | AKR1C3 (0.69) | ALDH1A1TDP1GLAAKR1C3TSHR | |
| SCHEMBL476911 | 0.82 | AKR1C3 (0.69) | ALDH1A1TDP1GLAAKR1C3TSHR | |
| SCHEMBL318840 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRKMT2ARARG | |
| SCHEMBL318839 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRKMT2ARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566900-B1 | COPOLYMERS FOR NEAR-INFRARED RADIATION-SENSITIVE COATING COMPOSITIONS FOR POSITIVE-WORKING THERMAL LITHOGRAPHIC PRINTING PLATES | MYLAN GROUP (VN) | 2016-02-17 | — | — | EP | claimed |
| US-20140221591-A1 | COPOLYMERS FOR NEAR-INFRARED RADIATION-SENSITIVE COATING COMPOSITIONS FOR POSITIVE-WORKING THERMAL LITHOGRAPHIC PRINTING PLATES | MYLAN GROUP (VN) | 2014-08-07 | — | — | US | claimed |
| EP-2566900-A2 | COPOLYMERS FOR NEAR-INFRARED RADIATION-SENSITIVE COATING COMPOSITIONS FOR POSITIVE-WORKING THERMAL LITHOGRAPHIC PRINTING PLATES | Mylan Group (VN) | 2013-03-13 | — | — | EP | claimed |
| WO-2011006265-A2 | COPOLYMERS FOR NEAR-INFRARED RADIATION-SENSITIVE COATING COMPOSITIONS FOR POSITIVE-WORKING THERMAL LITHOGRAPHIC PRINTING PLATES | MYLAN GROUP (VN) | 2011-01-20 | — | — | WO | claimed |
| US-5549807-A | Thermoplastic composites formed by electropolymerization of N-substituted methacrylamide monomers | THE UNIVERSITY OF CONNECTICUT (US) | 1996-08-27 | — | — | US | claimed |
| US-5238542-A | Onto electrically conductive filler | THE UNIVERSITY OF CONNECTICUT (US) | 1993-08-24 | — | — | US | claimed |
| EP-4074701-B1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | LG CHEMICAL LTD (KR) | 2023-12-13 | — | — | EP | disclosed |
| US-20230101389-A1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | LG CHEM, LTD. (KR) | 2023-03-30 | — | — | US | disclosed |
| CN-114901653-A | Novel amide derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2022-08-12 | — | — | CN | disclosed |
| WO-2021133038-A1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | 주식회사 엘지화학 | 2021-07-01 | — | — | WO | disclosed |
| CN-112955824-A | Developing roller, developing device, and image forming apparatus | 信越聚合物株式会社 | 2021-06-11 | — | — | CN | disclosed |
| US-10889146-B2 | Tire object provided with an elastomer layer made of a thermoplastic elastomer in the form of an (A-b-(a-methylstyrene-co-B))n-b-C block copolymer | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2021-01-12 | — | — | US | disclosed |
| CN-111527262-A | Heat sealable barrier coating for paperboard | 乔治亚太平洋漂白板有限公司 | 2020-08-11 | — | — | CN | disclosed |
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0862093-A1 | Low hardness conductive roll | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| US-5549807-A | Thermoplastic composites formed by electropolymerization of N-substituted methacrylamide monomers | THE UNIVERSITY OF CONNECTICUT (US) | 1996-08-27 | — | — | US | disclosed |
| US-5466357-A | THERMOPLASTIC MATRIX PREPREG COMPOSITE PRODUCT | THE UNIVERSITY OF CONNECTICUT (US) | 1995-11-14 | — | — | US | disclosed |
| US-5238542-A | Onto electrically conductive filler | THE UNIVERSITY OF CONNECTICUT (US) | 1993-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230101389-A1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | DGAT2, DGAT1, MOGAT2 | ALDH1A1 696/4885TDP1 3275/4885POLB 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.