Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21977108 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1LMNASMN1; SMN2CD44 | |
| SCHEMBL9225490 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL9001208 | 0.82 | SLC1A3 (0.55) | KDM4EALDH1A1LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL31732804 | 0.77 | GAA (0.52) | KDM4EALDH1A1LMNASMN1; SMN2OPRM1 | |
| SCHEMBL375390 | 0.77 | GAA (0.52) | KDM4EALDH1A1LMNASMN1; SMN2OPRM1 | |
| SCHEMBL11744143 | 0.75 | CD44 (0.50) | KDM4EALDH1A1LMNASMN1; SMN2CD44 | |
| SCHEMBL16000118 | 0.75 | NSD2 (0.64) | KDM4EALDH1A1LMNASMN1; SMN2NSD2 | |
| SCHEMBL3181504 | 0.74 | ALDH1A1 (0.53) | KDM4EALDH1A1LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL11133598 | 0.74 | L3MBTL1 (0.48) | KDM4EALDH1A1SMN1; SMN2CD44 | |
| SCHEMBL1522324 | 0.74 | CA2 (0.50) | KDM4EALDH1A1CD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674936-B2 | Ortho-substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-03-09 | — | — | US | disclosed |
| EP-1423379-B1 | ORTHO-SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2008-05-28 | — | — | EP | disclosed |
| US-7288554-B2 | Ortho-substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-30 | — | — | US | disclosed |
| US-20070249832-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | FMC CORPORATION | 2007-10-25 | — | — | US | disclosed |
| US-20040192731-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| EP-1423379-A1 | ORTHO-SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E.I. du Pont de Nemours and Company (US) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003016300-A1 | ORTHO-SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192731-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | DDT, ACHE, CBR1 | KDM4E 1228/4885ALDH1A1 819/4885LMNA 4794/4885 |
| US-20070249832-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | NR2C2, GRK6, NR0B2 | KDM4E 2842/4885ALDH1A1 3071/4885LMNA 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.