SCHEMBL3198441

SCHEMBL3198441

Cc1cccc(C)c1N=C1CCCc2cc3c(nc21)C(=Nc1c(C)cccc1C)CCC3

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.37
RAB9A P51151 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
ALOX12 P18054 1/20 0.32
MEN1 O00255 1/20 0.32
HSP90AA1 P07900 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
GAA P10253 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
NPC1 O15118 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13418972 1.00 MAPT (0.37) MAPTRAB9ANPSR1KDM4ELMNA
SCHEMBL3198438 1.00 MAPT (0.37) MAPTRAB9ANPSR1KDM4ELMNA
Hydrochloric Acid SCHEMBL3198202 0.97 MAPT (0.36) MAPTRAB9ANPSR1KDM4ELMNA
SCHEMBL12021102 0.83 RAB9A (0.36) MAPTRAB9ANPSR1KDM4ELMNA
SCHEMBL3195185 0.83 RAB9A (0.36) MAPTRAB9ANPSR1KDM4ELMNA
SCHEMBL12020994 0.81 MAPT (0.34) MAPTKDM4EKMT2AALDH1A1
SCHEMBL3209293 0.81 KDM4E (0.32) MAPTRAB9ANPSR1KDM4ELMNA
SCHEMBL14804878 0.81 KDM4E (0.32) MAPTRAB9ANPSR1KDM4ELMNA
Hydrochloric Acid SCHEMBL3208211 0.79 TAAR1 (0.31) KDM4ECYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL3193450 0.78 NPY5R (0.39) MAPTRAB9ANPSR1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773895-B1 CATALYSTS FOR OLEFIN POLYMERIZATION OR OLIGOMERIZATION DU PONT (US) 2011-12-28 EP disclosed
US-7683149-B2 Catalysts for olefin polymerization or oligomerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-23 US disclosed
US-20080287621-A1 Catalysts for olefin polymerization or oligomerization DUPONT POLYMERS, INC. 2008-11-20 US disclosed
US-7442819-B2 Catalysts for olefin polymerization or oligomerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-10-28 US disclosed
US-20060009597-A1 Catalysts for olefin polymerization or oligomerization DUPONT POLYMERS, INC. 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060009597-A1 Catalysts for olefin polymerization or oligomerization PPOX, HMOX1, NOD2 MAPT 525/4885RAB9A 4560/4885NPSR1 3230/4885
US-20080287621-A1 Catalysts for olefin polymerization or oligomerization PPOX, HMOX1, NOD2 MAPT 525/4885RAB9A 4560/4885NPSR1 3230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.