Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14804878 | 0.97 | KDM4E (0.32) | KDM4EALDH1A1CYP1A2GLACYP3A4 | |
| SCHEMBL3209293 | 0.97 | KDM4E (0.32) | KDM4EALDH1A1CYP1A2GLACYP3A4 | |
| Hydrochloric Acid SCHEMBL3198202 | 0.82 | MAPT (0.36) | KDM4E | |
| SCHEMBL13418972 | 0.79 | MAPT (0.37) | KDM4EALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL3198441 | 0.79 | MAPT (0.37) | KDM4EALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL3198438 | 0.79 | MAPT (0.37) | KDM4EALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL4056846 | 0.76 | GABRA1 (0.40) | TAAR1ALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL4056848 | 0.76 | GABRA1 (0.40) | TAAR1ALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL12020994 | 0.76 | MAPT (0.34) | KDM4EALDH1A1 | |
| SCHEMBL5589488 | 0.74 | GABRA1 (0.39) | CYP1A2CYP3A4HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773895-B1 | CATALYSTS FOR OLEFIN POLYMERIZATION OR OLIGOMERIZATION | DU PONT (US) | 2011-12-28 | — | — | EP | disclosed |
| US-7683149-B2 | Catalysts for olefin polymerization or oligomerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-03-23 | — | — | US | disclosed |
| US-20080287621-A1 | Catalysts for olefin polymerization or oligomerization | DUPONT POLYMERS, INC. | 2008-11-20 | — | — | US | disclosed |
| US-7442819-B2 | Catalysts for olefin polymerization or oligomerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-28 | — | — | US | disclosed |
| US-20060009597-A1 | Catalysts for olefin polymerization or oligomerization | DUPONT POLYMERS, INC. | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009597-A1 | Catalysts for olefin polymerization or oligomerization | PPOX, HMOX1, NOD2 | TAAR1 857/4885KDM4E 3147/4885ALDH1A1 3720/4885 |
| US-20080287621-A1 | Catalysts for olefin polymerization or oligomerization | PPOX, HMOX1, NOD2 | TAAR1 857/4885KDM4E 3147/4885ALDH1A1 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.