SCHEMBL3200901

SCHEMBL3200901

CC(C)(C)Oc1cccc(OC(C)(C)C)c1S(OS(=O)(=O)c1ccc(F)cc1F)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 1/20 0.34
ABCC8 Q09428 1/20 0.34
KCNJ11 Q14654 1/20 0.34
KCNJ8 Q15842 1/20 0.34
HTR2A P28223 4/20 0.33
HTR2C P28335 3/20 0.33
KCNH2 Q12809 2/20 0.33
MEN1 O00255 2/20 0.32
GFER P55789 2/20 0.32
KMT2A Q03164 2/20 0.32
CCR2 P41597 1/20 0.32
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTR6 P50406 2/20 0.31
TP53 P04637 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 3/20 0.31
HTR1A P08908 1/20 0.31
DRD2 P14416 1/20 0.31
HTR7 P34969 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3204664 0.92 ALDH1A1 (0.33) ABCC9ABCC8KCNJ11KCNJ8HTR2A
SCHEMBL3207047 0.85 HTR2A (0.34) ABCC9ABCC8KCNJ11KCNJ8HTR2A
SCHEMBL3190430 0.85 TSHR (0.33) ABCC9ABCC8KCNJ11KCNJ8HTR2A
SCHEMBL3203466 0.85 HTR6 (0.34) MEN1KMT2APKMHTR6GAA
SCHEMBL3197754 0.85 KMT2A (0.37) MEN1KMT2APKMHTR6ALDH1A1
SCHEMBL3195325 0.84 HTR2A (0.39) ABCC9ABCC8KCNJ11KCNJ8HTR2A
SCHEMBL3189928 0.84 TSHR (0.37) ABCC9ABCC8KCNJ11KCNJ8HTR2A
SCHEMBL3197589 0.83 ABCC9 (0.34) ABCC9ABCC8KCNJ11KCNJ8HTR2A
SCHEMBL2537987 0.83 HTR2A (0.41) ABCC9ABCC8KCNJ11KCNJ8HTR2A
SCHEMBL3181637 0.83 HTR6 (0.34) HTR6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed