SCHEMBL3207047

SCHEMBL3207047

CC(C)(C)Oc1ccc(S(OS(=O)(=O)c2ccc(F)cc2F)(c2ccccc2)c2ccccc2)c(OC(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.34
HTR2C P28335 4/20 0.34
ALDH1A1 P00352 2/20 0.33
HSD11B1 P28845 1/20 0.33
CCR2 P41597 1/20 0.33
ABCC9 O60706 1/20 0.32
ABCC8 Q09428 1/20 0.32
KCNJ11 Q14654 1/20 0.32
KCNJ8 Q15842 1/20 0.32
KCNH2 Q12809 2/20 0.32
PGR P06401 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
SLC6A4 P31645 1/20 0.30
PPARA Q07869 1/20 0.30
GAA P10253 1/20 0.30
PPARG P37231 1/20 0.30
CACNA1B Q00975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3204664 0.89 ALDH1A1 (0.33) HTR2AHTR2CALDH1A1CCR2ABCC9
SCHEMBL3194025 0.89 FFAR1 (0.35) HSD11B1
SCHEMBL3195325 0.89 HTR2A (0.39) HTR2AHTR2CALDH1A1HSD11B1ABCC9
SCHEMBL3193905 0.85 PKM (0.32) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL3200901 0.85 ABCC9 (0.34) HTR2AHTR2CALDH1A1CCR2ABCC9
SCHEMBL3197589 0.85 ABCC9 (0.34) HTR2AHTR2CALDH1A1CCR2ABCC9
SCHEMBL3195821 0.84 PPARA (0.31) PPARA
SCHEMBL3190430 0.82 TSHR (0.33) HTR2AHTR2CALDH1A1ABCC9ABCC8
SCHEMBL3182708 0.81 HSD11B1 (0.32) HSD11B1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL2537987 0.80 HTR2A (0.41) HTR2AHTR2CALDH1A1ABCC9ABCC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed