SCHEMBL3204664

SCHEMBL3204664

CC(C)(C)Oc1cc(OC(C)(C)C)c(S(OS(=O)(=O)c2ccc(F)cc2F)(c2ccccc2)c2ccccc2)c(OC(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
ABCC9 O60706 1/20 0.32
ABCC8 Q09428 1/20 0.32
KCNJ11 Q14654 1/20 0.32
KCNJ8 Q15842 1/20 0.32
HTR2A P28223 2/20 0.32
HTR2C P28335 2/20 0.32
KCNH2 Q12809 1/20 0.32
PIK3C3 Q8NEB9 1/20 0.31
CCR2 P41597 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3200901 0.92 ABCC9 (0.34) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL3207047 0.89 HTR2A (0.34) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL3190430 0.89 TSHR (0.33) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL3197589 0.87 ABCC9 (0.34) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL3182174 0.87 KMT2A (0.34)
SCHEMBL3195325 0.86 HTR2A (0.39) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL3192420 0.85 PKM (0.31) SMN1; SMN2GAA
SCHEMBL3182670 0.84 CA12 (0.32)
SCHEMBL3195099 0.81 HSD11B1 (0.32) ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL2537987 0.80 HTR2A (0.41) ALDH1A1ABCC9ABCC8KCNJ11KCNJ8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed