SCHEMBL3201041

SCHEMBL3201041

CCc1ccc(S(OS(=O)(=O)c2ccc(C(F)(F)F)cc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
F2 P00734 1/20 0.43
VDR P11473 1/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
HSD11B1 P28845 4/20 0.41
CYP3A4 P08684 3/20 0.40
CYP2C19 P33261 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
POLB P06746 2/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
AR P10275 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5412457 0.90 PPARG (0.40) ALDH1A1MAPTKDM4EF2VDR
SCHEMBL3182566 0.89 ALDH1A1 (0.51) ALDH1A1MAPTKDM4EF2VDR
SCHEMBL3139775 0.89 HSD11B1 (0.45) ALDH1A1MAPTKDM4EHSD11B1POLB
SCHEMBL3132687 0.89 HSD11B1 (0.45) ALDH1A1MAPTKDM4EHSD11B1POLB
SCHEMBL503702 0.89 HSD11B1 (0.45) ALDH1A1MAPTKDM4EHSD11B1POLB
SCHEMBL6282707 0.88 MAPT (0.43) ALDH1A1MAPTCYP3A4CYP2C19CYP2D6
SCHEMBL3201844 0.86 HSD11B1 (0.38) ALDH1A1MAPTKDM4EF2VDR
SCHEMBL3143580 0.85 BCHE (0.49) ALDH1A1VDRBCHEACHEHSD11B1
SCHEMBL3134871 0.85 HSD11B1 (0.47) ALDH1A1MAPTHSD11B1TSHRNR1H3
SCHEMBL3136049 0.85 BCHE (0.49) ALDH1A1VDRBCHEACHEHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed