Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861382 | 0.82 | MAPT (0.49) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL3195605 | 0.81 | RAB9A (0.48) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL3195600 | 0.79 | L3MBTL1 (0.46) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL2659085 | 0.79 | RAB9A (0.57) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL984297 | 0.78 | L3MBTL1 (0.57) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL9815841 | 0.78 | L3MBTL1 (0.57) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL11027172 | 0.78 | CASP3 (0.43) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL12617736 | 0.77 | NPC1 (0.60) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL11581518 | 0.77 | L3MBTL1 (0.55) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL4374949 | 0.77 | L3MBTL1 (0.59) | RAB9AMAPTL3MBTL1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745377-B2 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-06-29 | — | — | US | disclosed |
| US-7745377-B2 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-06-29 | — | — | US | disclosed |
| US-7662644-B2 | Use of specified fluorescent dyes to conjugate to antibody; detecting binding of an antibody to an antigen; antibody conjugate | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-16 | — | — | US | disclosed |
| US-7351797-B1 | Labeled peptides, and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351797-B1 | Labeled peptides, and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | disclosed |
| US-20070218502-A1 | LABELED PEPTIDES, PROTEINS AND ANTIBODIES AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | THE SCRIPPS RESEARCH INSTITUTE | 2007-09-20 | — | — | US | disclosed |
| US-7176037-B2 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-02-13 | — | — | US | disclosed |
| US-7176037-B2 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-02-13 | — | — | US | disclosed |
| US-20050287518-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE | 2005-12-29 | — | — | US | disclosed |
| US-6951947-B2 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-10-04 | — | — | US | disclosed |
| EP-1330471-A4 | LABELED PEPTIDES, AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | SCRIPPS RESEARCH INST (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20040067537-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | HAHN KLAUS M (US) | 2004-04-08 | — | — | US | disclosed |
| EP-1330471-A1 | LABELED PEPTIDES, AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-1301473-A2 | LABELED PEPTIDES, PROTEINS AND ANTIBODIES AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | The Scripps Research Institute (US) | 2003-04-16 | — | — | EP | disclosed |
| US-20020055133-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | SCRIPPS RESEARCH INSTITUTE, THE | 2002-05-09 | — | — | US | disclosed |
| WO-2002028890-A1 | LABELED PEPTIDES, AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-04-11 | — | — | WO | disclosed |
| WO-2002008245-A2 | LABELED PEPTIDES, PROTEINS AND ANTIBODIES AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055133-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | ARHGEF1, RHOC, CIT | RAB9A 185/4885MAPT 3198/4885L3MBTL1 2220/4885 |
| US-20040067537-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | CIT, RHOC, ARHGEF1 | RAB9A 228/4885MAPT 3165/4885L3MBTL1 2278/4885 |
| US-20070218502-A1 | LABELED PEPTIDES, PROTEINS AND ANTIBODIES AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | CIT, RHOC, ARHGEF1 | RAB9A 228/4885MAPT 3165/4885L3MBTL1 2278/4885 |
| US-20050287518-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | ARHGEF1, RHOC, CIT | RAB9A 185/4885MAPT 3198/4885L3MBTL1 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.