Sugi Predict

Sugi Predict / Compounds / SCHEMBL320277

SCHEMBL320277

SCHEMBL320277

CC(O)c1ccc(C#N)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 1/20 0.49
▸ CYP2A6 P11509 2/20 0.48
▸ CA2 P00918 2/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ CA12 O43570 1/20 0.48
▸ CA3 P07451 1/20 0.48
▸ CA6 P23280 1/20 0.48
▸ CA9 Q16790 1/20 0.48
▸ CA14 Q9ULX7 1/20 0.48
▸ CYP19A1 P11511 3/20 0.44
▸ MMP3 P08254 1/20 0.43
▸ ENPP2 Q13822 1/20 0.43
▸ NOS3 P29474 3/20 0.42
▸ NOS1 P29475 3/20 0.42
▸ KDM4E B2RXH2 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ GSK3B P49841 1/20 0.41
▸ SIRT2 Q8IXJ6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728041 1.00 PGR (0.49) PGRCYP2A6CA2ALDH1A1CA12
SCHEMBL342986 1.00 PGR (0.49) PGRCYP2A6CA2ALDH1A1CA12
SCHEMBL8019149 0.94 MMP3 (0.54) PGRCYP2A6CA2ALDH1A1CA12
SCHEMBL15981026 0.88 PARP15 (0.50) PGRALDH1A1CYP19A1MMP3KDM4E
SCHEMBL2296391 0.82 CYP2A6 (0.44) CYP2A6CA2ALDH1A1CA12CA3
SCHEMBL25920912 0.82 CYP2A6 (0.44) CYP2A6CA2ALDH1A1CA12CA3
SCHEMBL17902413 0.82 CYP2A6 (0.44) CYP2A6CA2ALDH1A1CA12CA3
SCHEMBL15617720 0.82 CYP2A6 (0.44) CYP2A6CA2ALDH1A1CA12CA3
SCHEMBL7799578 0.80 CYP2A6 (0.52) CYP2A6CA2ALDH1A1CA12CA3
SCHEMBL13557870 0.80 CYP2A6 (0.52) CYP2A6CA2ALDH1A1CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119491240-A Method for preparing benzyl carboxylic acid compound by taking carbon dioxide as raw material 哈尔滨工业大学（深圳） 2025-02-21 — — CN claimed
CN-113563759-B Graphene and nano-silver composite material and preparation method thereof 中国科学院山西煤炭化学研究所 2022-11-25 — — CN claimed
CN-113563759-A Graphene and nano-silver composite material and preparation method thereof 中国科学院山西煤炭化学研究所 2021-10-29 — — CN claimed
CN-111135161-A Application and preparation method of perfoliate knotweed herb extract with anti-tumor activity 谭竞 2020-05-12 — — CN claimed
CN-101503729-B Enzymatic resolution method of dl 1-phenylethanol compounds UNIV ZHEJIANG 2012-10-31 — — CN claimed
EP-4658656-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 — — EP disclosed
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-13 — — US disclosed
CN-119614529-A Short-chain dehydrogenase, engineering bacteria and application thereof in asymmetric reduction of potential chiral carbonyl compounds 杭州文德阶生物科技有限公司 2025-03-14 — — CN disclosed
WO-2024160276-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 — — WO disclosed
CN-117486660-A Preparation method of fluorine-containing phenylethane compound 国网安徽省电力有限公司电力科学研究院 2024-02-02 — — CN disclosed
US-20230391812-A1 RUTHENIUM COMPLEX, PRODUCTION METHOD OF THE COMPLEX, AND PRODUCTION METHOD OF OPTICALLY ACTIVE SECONDARY ALCOHOLS USING THE COMPLEX AS CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-12-07 — — US disclosed
US-20230285945-A1 CATALYST CONTAINING ACTIVATED CARBON ADSORBED WITH RUTHENIUM COMPLEX, AND METHOD FOR PRODUCING REDUCTION PRODUCT USING SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-09-14 — — US disclosed
WO-1996039137-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1996-12-12 — — WO disclosed
US-4061642-A AZO DYE INTERMEDIATES CASSELLA FARBWERKE MAINKUR AG (DT) 1977-12-06 — — US disclosed
US-3980659-A INSECTICIDES, INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-09-14 — — US disclosed
US-3956294-A AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-11 — — US disclosed
US-3954782-A 2,6-Hydrazino-3-pyridine carboxyamides CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 — — US disclosed
US-3954396-A MONOAZO CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 — — US disclosed
US-3947463-A Certain 2-amino-nicotinonitrile derivatives CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-30 — — US disclosed
US-3946024-A INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285945-A1 CATALYST CONTAINING ACTIVATED CARBON ADSORBED WITH RUTHENIUM COMPLEX, AND METHOD FOR PRODUCING REDUCTION PRODUCT USING SAME RRS1, POR, SCO2 PGR 2852/4885CYP2A6 518/4885CA2 244/4885
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES DGKG, DGKA, DGKK PGR 2125/4885CYP2A6 4672/4885CA2 3679/4885
US-20230391812-A1 RUTHENIUM COMPLEX, PRODUCTION METHOD OF THE COMPLEX, AND PRODUCTION METHOD OF OPTICALLY ACTIVE SECONDARY ALCOHOLS USING THE COMPLEX AS CATALYST ADH5, ADH1A, ADH1C PGR 2393/4885CYP2A6 243/4885CA2 2433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.