Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.50 |
| ▸ | CCR2 | P41597 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | HTR1F | P30939 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210431 | 1.00 | HSD11B1 (0.50) | HSD11B1CCR2HTR1AHTR1DHTR1B | |
| SCHEMBL31295138 | 0.83 | HPGDS (0.49) | HSD11B1CCR2HTR1AHTR1DHTR1B | |
| SCHEMBL3203565 | 0.83 | HPGDS (0.49) | HSD11B1CCR2HTR1AHTR1DHTR1B | |
| SCHEMBL31530773 | 0.82 | HPGDS (0.48) | HSD11B1CCR2HTR1AHTR1DHTR1B | |
| SCHEMBL2347633 | 0.78 | PDE10A (0.54) | CCR2HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3217354 | 0.77 | HTR1A (0.50) | CCR2HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3215983 | 0.77 | HTR1A (0.50) | CCR2HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL30909178 | 0.77 | HTR1F (0.65) | HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3257683 | 0.77 | HTR1F (0.65) | HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3319287 | 0.76 | HCAR2 (0.46) | HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029629-A1 | ACYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029629-A1 | ACYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | HTR6, HTR1A, HTR5A | HSD11B1 2163/4885CCR2 913/4885HTR1A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.