SCHEMBL320399

SCHEMBL320399

C[N+](C)(CCCCCC[N+](C)(C)Cc1ccc(C(=O)c2ccccc2)cc1)Cc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.58
SMN1; SMN2 Q16637 3/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
TP53 P04637 1/20 0.57
MAPK1 P28482 1/20 0.57
HTT P42858 4/20 0.55
PSMD14 O00487 1/20 0.46
HSP90AA1 P07900 1/20 0.46
MMP2 P08253 1/20 0.46
MC4R P32245 1/20 0.46
RAD52 P43351 1/20 0.46
ALDH1A1 P00352 4/20 0.45
SRD5A2 P31213 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
ATM Q13315 1/20 0.43
HPGD P15428 2/20 0.42
ACHE P22303 1/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL231434 0.98 DNM1 (0.59) DNM1SMN1; SMN2MEN1KMT2ATP53
Bromide SCHEMBL19971582 0.98 DNM1 (0.57) DNM1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL16731588 0.95 DNM1 (0.51) DNM1SMN1; SMN2MEN1KMT2ATP53
Bromide SCHEMBL11412610 0.93 DNM1 (0.70) DNM1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL485968 0.92 ALDH1A1 (0.50) DNM1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL16788930 0.91 DNM1 (0.59) DNM1SMN1; SMN2MEN1KMT2ATP53
Bromide SCHEMBL231675 0.90 ALDH1A1 (0.48) DNM1SMN1; SMN2MEN1KMT2ATP53
Iodide SCHEMBL20919878 0.89 DNM1 (0.58) DNM1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL14521789 0.87 DNM1 (0.50) DNM1SMN1; SMN2MEN1KMT2ATP53
Bromide SCHEMBL29669478 0.86 DNM1 (0.51) DNM1SMN1; SMN2MEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1503813-A1 SILANE COATING COMPOSITION SurModics, Inc. (US) 2005-02-09 EP claimed
US-6706408-B2 Silane coating composition SURMODICS, INC. 2004-03-16 US claimed
WO-2003097117-A1 SILANE COATING COMPOSITION SURMODICS, INC. (US) 2003-11-27 WO claimed
US-20030215649-A1 First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker SURMODICS, INC. 2003-11-20 US claimed
WO-2026090506-A1 MEDICAL DEVICE COATINGS AND METHODS SURMODICS, INC. (US) 2026-04-30 WO disclosed
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS SURMODICS INC (US) 2026-04-23 US disclosed
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE SURMODICS INC (US) 2026-04-23 US disclosed
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SURMODICS INC (US) 2026-04-09 US disclosed
US-12472288-B2 Lubricious coating for medical device SURMODICS, INC. (US) 2025-11-18 US disclosed
EP-4646241-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED DURABILITY SurModics, Inc. (US) 2025-11-12 EP disclosed
US-12441951-B2 Polyacrylic acid containing lubricious coatings for medical devices with enhanced properties SURMODICS, INC. (US) 2025-10-14 US disclosed
EP-4082598-B1 LOW-FRICTION SEALING DEVICES SURMODICS INC (US) 2025-10-01 EP disclosed
US-20070141365-A1 Silane Coating Compositions, Coating Systems, and Methods Surmodics Coatings, LLC 2007-06-21 US disclosed
EP-1503813-B1 SILANE COATING COMPOSITION SURMODICS INC (US) 2007-05-30 EP disclosed
US-20070054127-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS Surmodics Coatings, LLC 2007-03-08 US disclosed
WO-2007025059-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS SURMODICS, INC. (US) 2007-03-01 WO disclosed
EP-1503813-A1 SILANE COATING COMPOSITION SurModics, Inc. (US) 2005-02-09 EP disclosed
US-6706408-B2 Silane coating composition SURMODICS, INC. 2004-03-16 US disclosed
WO-2003097117-A1 SILANE COATING COMPOSITION SURMODICS, INC. (US) 2003-11-27 WO disclosed
US-20030215649-A1 First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker SURMODICS, INC. 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE MUC1, ADH1A, PTK2 DNM1 4737/4885SMN1; SMN2 1225/4885MEN1 3080/4885
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES CUTA, EED, SELP DNM1 4435/4885SMN1; SMN2 1841/4885MEN1 2578/4885
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS VCL, RAD54L, SELP DNM1 3349/4885SMN1; SMN2 978/4885MEN1 2678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.