Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28308414 | 0.78 | SMN1; SMN2 (0.41) | KDM4EMAPTJAK3ADRA1D | |
| SCHEMBL29574933 | 0.78 | SMN1; SMN2 (0.41) | KDM4EMAPTJAK3ADRA1D | |
| SCHEMBL7083112 | 0.73 | PARP1 (0.47) | PARP1KDM4EMAPT | |
| SCHEMBL14058648 | 0.72 | KDM4E (0.42) | PARP1KDM4EGAAMAPTADRA1D | |
| SCHEMBL8834886 | 0.71 | KDM4E (0.38) | KDM4EGAAMAPT | |
| SCHEMBL440740 | 0.70 | PARP1 (0.57) | PARP1KDM4ENNMTMAPT | |
| SCHEMBL5823962 | 0.70 | RIPK1 (0.40) | PARP1GAAMAPT | |
| SCHEMBL8521320 | 0.69 | PARP1 (0.39) | PARP1 | |
| Hydrochloric Acid SCHEMBL29152372 | 0.69 | PARP1 (0.55) | PARP1KDM4ENNMTMAPT | |
| SCHEMBL28805611 | 0.69 | KDM4E (0.38) | PARP1KDM4EGAAJAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016096942-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-23 | — | — | WO | disclosed |
| US-20160150782-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2016-06-02 | — | — | US | disclosed |
| EP-3019012-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2016-05-18 | — | — | EP | disclosed |
| US-9102623-B2 | Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use | BAYER CROPSCIENCE AG (DE) | 2015-08-11 | — | — | US | disclosed |
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| WO-2015004040-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-01-15 | — | — | WO | disclosed |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | ZIEMER FRANK (DE) | 2012-10-04 | — | — | US | disclosed |
| EP-2152077-A1 | USE OF PYRIDINE-2-OXY-3-CARBONAMIDES AS SAFENERS | Bayer CropScience AG (DE) | 2010-02-17 | — | — | EP | disclosed |
| EP-2144879-A2 | PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF | Bayer CropScience AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008131860-A2 | PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008131861-A1 | USE OF PYRIDINE-2-OXY-3-CARBONAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | WO | disclosed |
| EP-1987718-A1 | Utilisation of pyridine-2-oxy-3-carbon amides as safener | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| EP-1987717-A1 | Pyridon carboxamides, agents containing these but not impacting useful plants and method for their manufacture and application | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | CBR3, CBR1, CYP4Z1 | PARP1 1761/4885KDM4E 3015/4885NNMT 1819/4885 |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | CYC1, CYCS, CBR3 | PARP1 329/4885KDM4E 740/4885NNMT 543/4885 |
| US-20160150782-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | PDXK, PLPBP, PNPO | PARP1 1362/4885KDM4E 1838/4885NNMT 182/4885 |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | CYC1, PYCR1, CBR3 | PARP1 258/4885KDM4E 826/4885NNMT 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.