Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971361 | 0.82 | CA2 (0.53) | GAACA12CA1CA2CA9 | |
| SCHEMBL3096628 | 0.79 | — | — | |
| SCHEMBL818508 | 0.78 | HTR6 (0.50) | HTR6CYP3A4GAALMNAMPO | |
| SCHEMBL310696 | 0.75 | GAA (0.73) | CYP3A4GAACYP2C9CA12CA1 | |
| SCHEMBL28422858 | 0.75 | HTR6 (0.73) | HTR6CYP3A4GAALMNAMPO | |
| SCHEMBL3081661 | 0.73 | ALDH1A1 (0.49) | HTR6CYP3A4GAALMNAMPO | |
| SCHEMBL3781114 | 0.73 | ALDH1A1 (0.42) | HTR6CYP3A4GAALMNAMPO | |
| SCHEMBL3052955 | 0.71 | GAA (0.53) | HTR6CYP3A4GAALMNAMPO | |
| SCHEMBL9243675 | 0.71 | ALDH1A1 (0.73) | HTR6CYP3A4GAALMNAMPO | |
| SCHEMBL9580065 | 0.71 | HTR6 (0.41) | HTR6CYP3A4GAALMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683097-B2 | Topoisomerase inhibitors | Propharmacon Inc. (US) | 2010-03-23 | — | — | US | claimed |
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | claimed |
| US-7683097-B2 | Topoisomerase inhibitors | Propharmacon Inc. (US) | 2010-03-23 | — | — | US | disclosed |
| US-20070004701-A1 | Topoisomerase inhibitors | PROPHARMACON, INC. (US) | 2007-01-04 | — | — | US | disclosed |
| WO-2006022955-A2 | TOPOISOMERASE INHIBITORS | PROPHARMACON, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004701-A1 | Topoisomerase inhibitors | TOP1, TOP2A, TOP2B | HTR6 3720/4885CYP3A4 2589/4885GAA 704/4885 |
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | NFKBIA, IKBKB, CHUK | HTR6 3186/4885CYP3A4 4086/4885GAA 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.