Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223754 | 0.80 | ALDH1A1 (0.50) | ALDH1A1FNTAFNTBL3MBTL1KMT2A | |
| SCHEMBL149658 | 0.77 | TSHR (0.61) | KDM4EPOLBTSHRALOX15L3MBTL1 | |
| SCHEMBL20953940 | 0.77 | TSHR (0.61) | KDM4EPOLBTSHRALOX15L3MBTL1 | |
| SCHEMBL13425060 | 0.77 | KDM4E (0.36) | KDM4EPOLBTSHRALDH1A1ALOX15 | |
| SCHEMBL5035399 | 0.75 | TSHR (0.58) | KDM4EPOLBTSHRALOX15L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27983434 | 0.75 | TSHR (0.58) | KDM4EPOLBTSHRALOX15L3MBTL1 | |
| SCHEMBL4778780 | 0.75 | TSHR (0.42) | POLBTSHRALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL3314893 | 0.74 | ALDH1A1 (0.56) | KDM4EPOLBALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7116056 | 0.73 | CES2 (0.43) | KDM4EPOLBTSHRALDH1A1ALOX15 | |
| SCHEMBL3207192 | 0.72 | TSHR (0.50) | TSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | claimed |
| CN-101558106-B | Control of surface properties by chemical modification | ISIS INNOVATION | 2012-10-17 | — | — | CN | claimed |
| EP-2054465-B1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION (GB) | 2012-07-11 | — | — | EP | claimed |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | claimed |
| CN-101558106-A | Control of surface properties by chemical modification | ISIS INNOVATION (GB) | 2009-10-14 | — | — | CN | claimed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | claimed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | claimed |
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| CN-101558106-B | Control of surface properties by chemical modification | ISIS INNOVATION | 2012-10-17 | — | — | CN | disclosed |
| EP-2054465-B1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION (GB) | 2012-07-11 | — | — | EP | disclosed |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | disclosed |
| CN-101558106-A | Control of surface properties by chemical modification | ISIS INNOVATION (GB) | 2009-10-14 | — | — | CN | disclosed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ITGB2, ITGA2B, ITGB1 | KDM4E 2738/4885POLB 1216/4885TSHR 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.