SCHEMBL3207564

SCHEMBL3207564

COC(=O)c1cccc2c(C)cccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 4/20 0.58
LMNA P02545 2/20 0.50
TSHR P16473 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2A6 P11509 1/20 0.50
ALDH1A1 P00352 3/20 0.48
CFTR P13569 1/20 0.48
HSD17B10 Q99714 1/20 0.48
BRD4 O60885 2/20 0.47
KDM4E B2RXH2 4/20 0.47
POLB P06746 1/20 0.47
ATM Q13315 1/20 0.47
PSMD14 O00487 1/20 0.46
MYC P01106 1/20 0.46
CREBBP Q92793 1/20 0.46
KMT2A Q03164 2/20 0.44
MAPT P10636 1/20 0.44
ALOX12 P18054 1/20 0.44
MEN1 O00255 1/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70429 0.90 LMNA (0.59) NR4A2LMNATSHRALDH1A1CFTR
SCHEMBL870574 0.89 BRD4 (0.51) NR4A2LMNATSHRCYP1A2ALDH1A1
SCHEMBL3230050 0.82 NR4A2 (0.53) NR4A2LMNATSHRALDH1A1CFTR
SCHEMBL19258188 0.81 NR4A2 (0.55) NR4A2LMNATSHRALDH1A1CFTR
SCHEMBL70381 0.81 BRD4 (0.59) NR4A2LMNATSHRALDH1A1CFTR
SCHEMBL29434198 0.81 BRD4 (0.59) NR4A2LMNATSHRALDH1A1CFTR
SCHEMBL1772394 0.81 MAPT (0.50) NR4A2LMNATSHRCYP1A2ALDH1A1
SCHEMBL23909597 0.81 ALDH1A1 (0.53) NR4A2LMNATSHRALDH1A1CFTR
SCHEMBL9300933 0.81 LMNA (0.66) NR4A2LMNATSHRALDH1A1CFTR
SCHEMBL23909537 0.81 LMNA (0.50) NR4A2LMNATSHRALDH1A1CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111936576-B Thermoplastic resin composition and molded product made therefrom 乐天化学株式会社 2023-10-17 CN disclosed
CN-111936576-A Thermoplastic resin composition and molded product made therefrom 乐天化学株式会社 2020-11-13 CN disclosed
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-01-28 US disclosed
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-14 US disclosed
EP-2135671-B1 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst MITSUBISHI GAS CHEMICAL CO (JP) 2015-03-04 EP disclosed
CN-103657631-A Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst MITSUBISHI GAS CHEMICAL CO 2014-03-26 CN disclosed
CN-101632925-B Catalyst and process for producing carboxylic acid and/or carboxylic acid anhydride using the same MITSUBISHI GAS CHEMICAL CO 2014-02-26 CN disclosed
US-8357625-B2 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-22 US disclosed
EP-2305769-A2 Emitting material and organic light emitting diode using the same LG Chem, Ltd. (KR) 2011-04-06 EP disclosed
US-20100036138-A1 CATALYST AND METHOD FOR PRODUCING CARBOXYLIC ACID AND/OR CARBOXYLIC ANHYDRIDE IN THE PRESENCE OF THE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-11 US disclosed
CN-101632925-A Catalyst and process for producing carboxylic acid and/or carboxylic acid anhydride using the same MITSUBISHI GAS CHEMICAL CO 2010-01-27 CN disclosed
EP-2135671-A2 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst Mitsubishi Gas Chemical Company, Inc. (JP) 2009-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 NR4A2 1739/4885LMNA 1841/4885TSHR 1122/4885
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 NR4A2 1739/4885LMNA 1841/4885TSHR 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.