Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15475170 | 0.80 | CALM1 (0.30) | CALM1 | |
| SCHEMBL10742451 | 0.79 | ELANE (0.36) | ALDH1A1TSHRHSD17B10ALOX15APP | |
| SCHEMBL8128063 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10ALOX15TERT | |
| SCHEMBL11643095 | 0.78 | EGFR (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2040143 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10KDM4EGAA | |
| SCHEMBL12466363 | 0.76 | MTNR1A (0.35) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1419133 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10ALOX15APP | |
| SCHEMBL4858324 | 0.73 | CYP3A4 (0.33) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10399292 | 0.72 | CYP2C19 (0.45) | ALDH1A1TSHRCALM1KDM4EGAA | |
| SCHEMBL11644681 | 0.72 | NR5A1 (0.37) | ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | claimed |
| US-7402589-B2 | Tri-substituted ureas as cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-22 | — | — | US | claimed |
| US-20050245555-A1 | Tri-substituted ureas as cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-03 | — | — | US | claimed |
| WO-2021006267-A1 | SALT OF PYRAZOLE DERIVATIVE AND PREPARATION OF PYRAZOLE DERIVATIVE | グリーン・テック株式会社 | 2021-01-14 | — | — | WO | disclosed |
| WO-2020235582-A1 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR MOTOR NEURON DISEASE | グリーン・テック株式会社 (JP) | 2020-11-26 | — | — | WO | disclosed |
| EP-3323816-A1 | NOVEL PYRAZOLE DERIVATIVE | Green Tech Co., Ltd. (JP) | 2018-05-23 | — | — | EP | disclosed |
| US-9399635-B2 | Pyrazole derivative | GREEN TECH CO., LTD. (JP) | 2016-07-26 | — | — | US | disclosed |
| US-8962674-B2 | Curcumin derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20140088029-A1 | NOVEL PYRAZOLE DERIVATIVE | PHARMA EIGHT CO., LTD. (JP) | 2014-03-27 | — | — | US | disclosed |
| EP-2698368-A1 | NOVEL PYRAZOLE DERIVATIVE | Pharma Eight Co. Ltd (JP) | 2014-02-19 | — | — | EP | disclosed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |
| US-4966983-A | PRESSURE OR HEAT SENSITIVE ELEMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4910207-A | Antipsychotic agent | NOVARTIS AG (CH) | 1990-03-20 | — | — | US | disclosed |
| US-4843145-A | Catalytic polymerization of CO/olefin with ortho polar substituted aryl bidentate p ligand | SHELL OIL COMPANY (US) | 1989-06-27 | — | — | US | disclosed |
| US-4841050-A | Carbazole containing benzopyrans | BASF AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0236973-B1 | BENZOPYRANES AND THEIR USE IN A RECORDING SYSTEM | BASF Aktiengesellschaft (DE) | 1989-06-14 | — | — | EP | disclosed |
| US-4803199-A | SEROTONIN ANTAGONIST, ANALGESIC ANTIARRHYTHMIC AGENTS | NOVARTIS AG (CH) | 1989-02-07 | — | — | US | disclosed |
| EP-0236973-A2 | Benzopyranes and their use in a recording system | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |
| WO-1984000166-A1 | BENZOIC ACID PIPERIDYL ESTER DERIVATIVES AND METHOD OF PRODUCTION AND UTILIZATION THEREOF | SANDOZ AG (CH) | 1984-01-19 | — | — | WO | disclosed |
| US-4119776-A | Vinyl phthalide color formers | NCR CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | TUBB4A 543/4885TUBB 800/4885TUBA3C 1358/4885 |
| US-20050245555-A1 | Tri-substituted ureas as cytokine inhibitors | IL1B, IL1A, IL6 | TUBB4A 3492/4885TUBB 2461/4885TUBA3C 3287/4885 |
| US-20140088029-A1 | NOVEL PYRAZOLE DERIVATIVE | PSEN2, MAPT, PSEN1 | TUBB4A 357/4885TUBB 222/4885TUBA3C 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.