Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 3/20 | 0.35 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999696 | 0.88 | TRPV1 (0.44) | PDE10ATAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL3223116 | 0.86 | PDE10A (0.41) | PDE10ATAS1R3TAS1R1NPSR1TAS1R2 | |
| SCHEMBL3219949 | 0.80 | ALDH1A1 (0.53) | TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL3219218 | 0.77 | TAS1R3 (0.60) | TAS1R3TAS1R1TAS1R2ACHE | |
| SCHEMBL3210493 | 0.77 | ALDH1A1 (0.62) | TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL22623413 | 0.75 | KDM4E (0.48) | PDE10ATAS1R3TAS1R1NPSR1TAS1R2 | |
| SCHEMBL6369376 | 0.73 | EPHX2 (0.46) | PDE10ATAS1R3TAS1R1NPSR1TAS1R2 | |
| SCHEMBL14040822 | 0.73 | ALDH1A1 (0.43) | PDE10ATAS1R3TAS1R1NPSR1TAS1R2 | |
| SCHEMBL3209919 | 0.73 | ALDH1A1 (0.43) | PDE10ATAS1R3TAS1R1NPSR1TAS1R2 | |
| SCHEMBL3209469 | 0.72 | PDE10A (0.41) | PDE10ATAS1R3TAS1R1TAS1R2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | PDE10A 1000/4885TAS1R3 816/4885TAS1R1 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.