Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209924 | 0.88 | PDE10A (0.41) | PDE10ATAS1R3TAS1R1TAS1R2ACHE | |
| SCHEMBL3219218 | 0.82 | TAS1R3 (0.60) | TAS1R3TAS1R1TAS1R2ACHEDRD4 | |
| SCHEMBL3219949 | 0.80 | ALDH1A1 (0.53) | TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL3210493 | 0.77 | ALDH1A1 (0.62) | TAS1R3TAS1R1TAS1R2LMNAALDH1A1 | |
| SCHEMBL4711698 | 0.76 | TRPV1 (0.53) | TRPV1PDE10ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16709695 | 0.75 | TRPV1 (0.52) | TRPV1PDE10ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3223116 | 0.75 | PDE10A (0.41) | TRPV1PDE10ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3209469 | 0.74 | PDE10A (0.41) | PDE10ATAS1R3TAS1R1TAS1R2ACHE | |
| SCHEMBL1999695 | 0.72 | KMT2A (0.46) | TRPV1PDE10ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4016100 | 0.71 | TRPV1 (0.51) | TRPV1PDE10ATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309739-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2012-11-13 | — | — | US | disclosed |
| US-20110218341-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-09-08 | — | — | US | disclosed |
| US-7960310-B2 | Method of combating and controlling insects | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-14 | — | — | US | disclosed |
| EP-1919886-B1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| US-20080300285-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| EP-1919886-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007020377-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300285-A1 | Chemical Compounds | CHRM5, OR10J3, CHRM3 | TRPV1 2039/4885PDE10A 1911/4885TAS1R3 34/4885 |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | TRPV1 193/4885PDE10A 1000/4885TAS1R3 816/4885 |
| US-20110218341-A1 | CHEMICAL COMPOUNDS | OR10J3, NR0B1, NR0B2 | TRPV1 2233/4885PDE10A 2389/4885TAS1R3 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.