SCHEMBL3211263

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4567002	0.88	MDM2 (0.50)	HDAC8PTPN1ERN1MAOBMAOA
	SCHEMBL1963431	0.88	HDAC8 (0.52)	HDAC8PTPN1ERN1MAOBMAOA
	SCHEMBL865350	0.87	MAOA (0.58)	HDAC8PTPN1ERN1MAOBMAOA
	SCHEMBL1311076	0.86	HDAC8 (0.65)	HDAC8ERN1MAOBNPC1KDM4E
	SCHEMBL1445747	0.85	MAOB (0.50)	HDAC8PTPN1ERN1MAOBMAOA
	SCHEMBL3208391	0.84	HDAC8 (0.64)	HDAC8KDM4ELMNAMAPTALDH1A1
	SCHEMBL3208404	0.84	HDAC8 (0.64)	HDAC8KDM4ELMNAMAPTALDH1A1
	SCHEMBL435043	0.83	ALDH1A1 (0.61)	HDAC8PTPN1ERN1MAOBMAOA
	SCHEMBL3370062	0.82	MAOB (0.52)	HDAC8PTPN1ERN1MAOBMAOA
	SCHEMBL3208113	0.82	KDM4E (0.44)	HDAC8MAOBMAOANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.