Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.45 |
| ▸ | CA9 | Q16790 | 6/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | FHIT | P49789 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216663 | 0.90 | ALDH1A1 (0.45) | CA12CA9CA1CA2TSHR | |
| SCHEMBL3205561 | 0.86 | CA1 (0.44) | CA12CA9CA1CA2TSHR | |
| SCHEMBL4373945 | 0.86 | CA1 (0.47) | CA12CA9CA1CA2TSHR | |
| SCHEMBL3207148 | 0.85 | CA1 (0.49) | CA12CA9CA1CA2TSHR | |
| SCHEMBL3218236 | 0.84 | TSHR (0.43) | CA12CA9CA1CA2TSHR | |
| SCHEMBL3212068 | 0.84 | CA2 (0.46) | CA12CA9CA1CA2TSHR | |
| SCHEMBL3206602 | 0.84 | CA1 (0.45) | CA12CA9CA1CA2TSHR | |
| SCHEMBL3205576 | 0.84 | CA1 (0.42) | CA12CA9CA1CA2TSHR | |
| SCHEMBL27477316 | 0.84 | CA1 (0.42) | CA12CA9CA1CA2TSHR | |
| SCHEMBL3215200 | 0.80 | CA12 (0.41) | CA12CA9CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858805-B2 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7642221-B2 | herbicides; preparation from chemical intermediates; treating the crops | BAYER AKTIENGESELLSCHAFT (DE) | 2010-01-05 | — | — | US | disclosed |
| US-7625841-B2 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2009-12-01 | — | — | US | disclosed |
| EP-1443822-B1 | SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| US-20080269061-A1 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
| US-7410933-B2 | Substituted thiene-3-ylsulphonylamino(thio)carbonyl-triazolin(thi)ones | BAYER CROPSCIENCE AG (DE) | 2008-08-12 | — | — | US | disclosed |
| CN-1324964-C | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(thi)ones | BAYER CROPSCIENCE AG (DE) | 2007-07-11 | — | — | CN | disclosed |
| US-6964939-B1 | Substituted thiene-3-yl-sulfonyl amino(thio)carbonyl-triazolin(thi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-15 | — | — | US | disclosed |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | US | disclosed |
| CN-1578625-A | Substituted thiophen-3-yl-sulfonylamino carbonyl-triazolin (thi) ones | BAYER CROPSCIENCE AG (DE) | 2005-02-09 | — | — | CN | disclosed |
| US-20050014809-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(thi)ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
| EP-1443822-A1 | SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer CropScience AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| EP-1200426-B1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003037086-A1 | SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2003-05-08 | — | — | WO | disclosed |
| EP-1200426-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer Aktiengesellschaft (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005788-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014809-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(thi)ones | DDT, TARS2, TST | CA12 4554/4885CA9 3872/4885CA1 3788/4885 |
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, CCNE2 | CA12 2976/4885CA9 3516/4885CA1 3440/4885 |
| US-20080269061-A1 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones | DDT, NAT1, TARS2 | CA12 4640/4885CA9 3870/4885CA1 3846/4885 |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, SULT2A1 | CA12 3954/4885CA9 3578/4885CA1 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.