Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.56 |
| ▸ | CTSS | P25774 | 6/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 7/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KYNU | Q16719 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211516 | 1.00 | CTSL (0.56) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL2745896 | 1.00 | CTSL (0.56) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL18455295 | 0.92 | CTSL (0.53) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL16346611 | 0.90 | KYNU (0.59) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL24103408 | 0.85 | CTSK (0.62) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL31054911 | 0.84 | CTSL (0.48) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL29399827 | 0.84 | CTSL (0.54) | CTSLCTSSCTSBCTSKALDH1A1 | |
| SCHEMBL6440666 | 0.84 | CTSL (0.64) | CTSLCTSSCTSBCTSKALDH1A1 | |
| SCHEMBL6440663 | 0.84 | CTSL (0.64) | CTSLCTSSCTSBCTSKALDH1A1 | |
| SCHEMBL31528405 | 0.84 | CTSK (0.55) | CTSLCTSSCTSBCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063013-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063013-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | CTSS, CTSB, CTSZ | CTSL 8/4885CTSS 1/4885CTSB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.