Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 4/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.49 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | ROS1 | P08922 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | MELK | Q14680 | 1/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.49 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910965 | 0.86 | ADK (0.58) | ADKCDK1CDK2DOT1LDCLK1 | |
| SCHEMBL6910971 | 0.86 | ADK (0.58) | ADKCDK1CDK2DOT1LDCLK1 | |
| SCHEMBL11840649 | 0.83 | ADK (0.68) | ADKCDK1CDK2DOT1LDCLK1 | |
| SCHEMBL3490107 | 0.83 | ATG7 (0.52) | ADKCDK1CDK2DOT1LDCLK1 | |
| SCHEMBL6910977 | 0.82 | ADK (0.65) | ADKCDK1CDK2DOT1LDCLK1 | |
| SCHEMBL6910983 | 0.82 | ADK (0.65) | ADKCDK1CDK2DOT1LDCLK1 | |
| Hydrochloric Acid SCHEMBL31238488 | 0.82 | ADK (0.52) | ADKCDK1CDK2DOT1LDCLK1 | |
| SCHEMBL7213421 | 0.76 | ALDH1A1 (0.57) | ADKDOT1LLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6912039 | 0.73 | ALDH1A1 (0.55) | ADKDOT1LLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6912032 | 0.73 | ALDH1A1 (0.55) | ADKDOT1LLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087388-A1 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | KOTRA LAKSHMI P | 2010-04-08 | — | — | US | disclosed |
| US-20100056468-A1 | Pyrimidine Derivatives As Anticancer Agents | UNIVERSITY HEALTH NETWORK (CA) | 2010-03-04 | — | — | US | disclosed |
| WO-2008083465-A1 | PYRIMIDINE DERIVATIVES AS ANTICANCER AGENTS | UNIVERSITY HEALTH NETWORK (CA) | 2008-07-17 | — | — | WO | disclosed |
| WO-2007038860-A2 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056468-A1 | Pyrimidine Derivatives As Anticancer Agents | DPYD, TYMP, TYMS | ADK 1394/4885CDK1 352/4885CDK2 105/4885 |
| US-20100087388-A1 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | ITPA, DUT, MAOA | ADK 624/4885CDK1 460/4885CDK2 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.