SCHEMBL358648

SCHEMBL358648

CC1(C)C(C=O)C1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
APLNR P35414 1/20 0.32
UGT2B7 P16662 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515780 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL2692874 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL8037708 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL3247829 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL3216533 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL11136789 0.80 LMNA (0.37) LMNA
SCHEMBL7064292 0.80 LMNA (0.37) LMNA
SCHEMBL3678270 0.79 UGT2B7 (0.32) LMNAUGT2B7
SCHEMBL3658221 0.79 UGT2B7 (0.32) LMNAUGT2B7
SCHEMBL11055234 0.79 UGT2B7 (0.32) LMNAUGT2B7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418197-B1 PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP claimed
US-8461370-B2 Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-06-11 US claimed
EP-2418197-A1 PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF Sumitomo Chemical Company, Limited (JP) 2012-02-15 EP claimed
US-20120016150-A1 Process for Producing 3-(2-Cyano-1-propenyl)-2,2- Dimethylcyclopropanecarboxylic Acid or Salt Thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US claimed
EP-1463706-B1 PROCESS FOR PRODUCTION OF 3,3-DIMETHYL-2-FORMYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVES SUMITOMO CHEMICAL CO (JP) 2008-02-27 EP claimed
US-7262320-B2 Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-28 US claimed
US-20050090685-A1 Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-04-28 US claimed
EP-1463706-A1 PROCESS FOR PRODUCTION OF 3,3-DIMETHYL-2-FORMYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVES Sumitomo Chemical Company, Limited (JP) 2004-10-06 EP claimed
WO-2003059861-A1 PROCESS FOR PRODUCTION OF 3,3-DIMETHYL-2-FORMYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-24 WO claimed
EP-0274314-B1 PROCESS FOR THE PREPARATION OF PENTAFLUOROPHENYLMETHYL 2,2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLATE, AND ITS USE IN THE SYNTHESIS OF PESTICIDAL PRODUCTS ROUSSEL-UCLAF (FR) 1990-11-07 EP claimed
EP-0030887-B1 IMINES DERIVED FROM ESTERS OF 3-FORMYL-CYCLOPROPANE-1-CARBOXYLIC ACIDS, THEIR PREPARATIONS, THEIR USE IN THE PREPARATION OF CORRESPONDING 3-VINYL-SUBSTITUTED ESTERS ROUSSEL-UCLAF (FR) 1984-01-18 EP claimed
EP-0095794-A1 Esters of 2,2-dimethyl-3-formyl-1-cyclopropane-carboxylic acid ROUSSEL-UCLAF (FR) 1983-12-07 EP claimed
EP-0022971-B1 PROCESS FOR THE PREPARATION OF 3-(2,2-DICHLOROVINYL)-2,2-DIMETHYL-CYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES BAYER AG (DE) 1983-03-16 EP claimed
EP-0002849-B1 PROCESS FOR THE PREPARATION OF DI-(HALO)-VINYL COMPOUNDS AND DI-(HALO)-VINYL COMPOUNDS PRODUCED THEREBY SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-01-27 EP claimed
US-4312817-A Imino derivatives ROUSSEL UCLAF (FR) 1982-01-26 US claimed
US-4296241-A Preparation of 3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 1981-10-20 US claimed
EP-0031041-A2 Pyrethroids and their preparation, their pesticidal composition; intermediates and their preparation Montedison S.p.A. (IT) 1981-07-01 EP claimed
EP-0030887-A2 Imines derived from esters of 3-formyl-cyclopropane-1-carboxylic acids, their preparations, their use in the preparation of corresponding 3-vinyl-substituted esters ROUSSEL-UCLAF (FR) 1981-06-24 EP claimed
EP-0002849-A1 Process for the preparation of di-(halo)-vinyl compounds and di-(halo)-vinyl compounds produced thereby SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-07-11 EP claimed
US-4014918-A Process for the preparation of cyclopropane derivatives and compounds produced therein ROUSSEL-UCLAF (FR) 1977-03-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090685-A1 Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives ADSL, CMPK1, MRPL21 LMNA 4209/4885APLNR 1708/4885UGT2B7 706/4885
US-20120016150-A1 Process for Producing 3-(2-Cyano-1-propenyl)-2,2- Dimethylcyclopropanecarboxylic Acid or Salt Thereof CPS1, PCCA, PKD1 LMNA 1251/4885APLNR 573/4885UGT2B7 3112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.