Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515780 | 1.00 | LMNA (0.33) | LMNAAPLNRUGT2B7KMT2A | |
| SCHEMBL8037708 | 1.00 | LMNA (0.33) | LMNAAPLNRUGT2B7KMT2A | |
| SCHEMBL3247829 | 1.00 | LMNA (0.33) | LMNAAPLNRUGT2B7KMT2A | |
| SCHEMBL3216533 | 1.00 | LMNA (0.33) | LMNAAPLNRUGT2B7KMT2A | |
| SCHEMBL358648 | 1.00 | LMNA (0.33) | LMNAAPLNRUGT2B7KMT2A | |
| SCHEMBL11136789 | 0.80 | LMNA (0.37) | LMNA | |
| SCHEMBL7064292 | 0.80 | LMNA (0.37) | LMNA | |
| SCHEMBL3678270 | 0.79 | UGT2B7 (0.32) | LMNAUGT2B7 | |
| SCHEMBL3658221 | 0.79 | UGT2B7 (0.32) | LMNAUGT2B7 | |
| SCHEMBL11055234 | 0.79 | UGT2B7 (0.32) | LMNAUGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132168-B1 | ESTERS OF CYCLOPROPANECARBOXYLIC ACIDS BEARING A CYANO GROUP, PREPARATION PROCESS AND INTERMEDIATES, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1987-06-16 | — | — | EP | claimed |
| EP-1970369-B1 | METHOD FOR PRODUCING PURIFIED FORMYLCYCLOPROPANE COMPOUND AND INTERMEDIATE OF SUCH FORMYLCYCLOPROPANE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2013-09-25 | — | — | EP | disclosed |
| US-8168816-B2 | Method for producing purified formylcyclopropane compound and intermediate of such formylcyclopropane compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20100305353-A1 | METHOD FOR PRODUCING PURIFIED FORMYLCYCLOPROPANE COMPOUND AND INTERMEDIATE OF SUCH FORMYLCYCLOPROPANE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-02 | — | — | US | disclosed |
| CN-101506142-A | Process for production of trans-2,2-dimethyl- 3-formylcyclopropane carboxylic acid ester | SUMITOMO CHEMICAL CO (JP) | 2009-08-12 | — | — | CN | disclosed |
| EP-2053037-A1 | PROCESS FOR PRODUCTION OF TRANS-2,2-DIMETHYL- 3-FORMYLCYCLOPROPANE CARBOXYLIC ACID ESTER | Sumitomo Chemical Company, Limited (JP) | 2009-04-29 | — | — | EP | disclosed |
| EP-1970369-A1 | METHOD FOR PRODUCING PURIFIED FORMYLCYCLOPROPANE COMPOUND AND INTERMEDIATE OF SUCH FORMYLCYCLOPROPANE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-09-17 | — | — | EP | disclosed |
| EP-1463706-B1 | PROCESS FOR PRODUCTION OF 3,3-DIMETHYL-2-FORMYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVES | SUMITOMO CHEMICAL CO (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-7262320-B2 | Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20050090685-A1 | Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| US-4996349-A | Reducing dioxolane diester to dialdehyde, adding ester using organic phosphorus compound, reacting with gem-dimethylcyclo-propanation reagent, hydrolyzing, cleaving | ROUSSEL UCLAF (FR) | 1991-02-26 | — | — | US | disclosed |
| EP-0305289-A1 | Enantioselective process for preparing derivatives of trans- or cis-hemicaronaldehyde, and intermediates obtained | ROUSSEL-UCLAF (FR) | 1989-03-01 | — | — | EP | disclosed |
| EP-0162538-A2 | Cyclopropane derivates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-27 | — | — | EP | disclosed |
| US-4482731-A | Process for the preparation of trans-3-(z-2-chloro-2-aryl-vinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid derivatives, and the use of intermediate products in agents for compating pests | BAYER AKTIENGESELLSCHAFT (DE) | 1984-11-13 | — | — | US | disclosed |
| US-4440947-A | Preparation of substituted alpha-halogeno-propionic acids and their derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1984-04-03 | — | — | US | disclosed |
| US-4435597-A | Preparation of caronaldehyde acid and derivatives thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-06 | — | — | US | disclosed |
| US-4206140-A | INSECTICIDES, ANTHELMINTICS | ROUSSEL UCLAF (FR) | 1980-06-03 | — | — | US | disclosed |
| US-4101574-A | Cyclopropanecarboxylic acid chlorides | ROUSSEL UCLAF (FR) | 1978-07-18 | — | — | US | disclosed |
| US-4014918-A | Process for the preparation of cyclopropane derivatives and compounds produced therein | ROUSSEL-UCLAF (FR) | 1977-03-29 | — | — | US | disclosed |
| US-3997586-A | Cyclopropanecarboxylic acids and esters | ROUSSEL-UCLAF (FR) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305353-A1 | METHOD FOR PRODUCING PURIFIED FORMYLCYCLOPROPANE COMPOUND AND INTERMEDIATE OF SUCH FORMYLCYCLOPROPANE COMPOUND | FPR1, FPR2, DHPS | LMNA 4220/4885APLNR 1576/4885UGT2B7 2075/4885 |
| US-20050090685-A1 | Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives | ADSL, CMPK1, MRPL21 | LMNA 4209/4885APLNR 1708/4885UGT2B7 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.