SCHEMBL515780

SCHEMBL515780

CC1(C)[C@H](C=O)[C@H]1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
APLNR P35414 1/20 0.32
UGT2B7 P16662 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2692874 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL8037708 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL3247829 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL3216533 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL358648 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL11136789 0.80 LMNA (0.37) LMNA
SCHEMBL7064292 0.80 LMNA (0.37) LMNA
SCHEMBL3678270 0.79 UGT2B7 (0.32) LMNAUGT2B7
SCHEMBL3658221 0.79 UGT2B7 (0.32) LMNAUGT2B7
SCHEMBL11055234 0.79 UGT2B7 (0.32) LMNAUGT2B7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0132168-B1 ESTERS OF CYCLOPROPANECARBOXYLIC ACIDS BEARING A CYANO GROUP, PREPARATION PROCESS AND INTERMEDIATES, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1987-06-16 EP claimed
CN-118063315-A Method for preparing Z-meta-chrysanthemate 江苏扬农化工股份有限公司 2024-05-24 CN disclosed
EP-2552883-B1 PYRETHRINOID-TYPE ESTERS AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2014-12-24 EP disclosed
EP-2412702-B1 METHOD FOR PRODUCING CYCLOPROPANECARBOXYLIC ACID ESTER SUMITOMO CHEMICAL CO (JP) 2014-12-03 EP disclosed
EP-2114871-B1 A CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2014-07-30 EP disclosed
EP-2418197-B1 PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
US-8614241-B2 Ester compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-24 US disclosed
US-8575213-B2 Pyrethrinoid-type esters as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-11-05 US disclosed
EP-1970369-B1 METHOD FOR PRODUCING PURIFIED FORMYLCYCLOPROPANE COMPOUND AND INTERMEDIATE OF SUCH FORMYLCYCLOPROPANE COMPOUND SUMITOMO CHEMICAL CO (JP) 2013-09-25 EP disclosed
US-8530669-B2 Ester compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-09-10 US disclosed
EP-0305289-A1 Enantioselective process for preparing derivatives of trans- or cis-hemicaronaldehyde, and intermediates obtained ROUSSEL-UCLAF (FR) 1989-03-01 EP disclosed
US-4760143-A Contining pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-07-26 US disclosed
US-4661488-A Pyrimidine substituted-2,2-dimethylcyclopropane carboxylates useful for combating insect and acarine pests at a locus IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-28 US disclosed
EP-0118873-B1 ACARICIDAL DIFLUOROETHENYLCYCLOPROPANECARBOXYLATES FMC Corporation (US) 1986-06-18 EP disclosed
EP-0162538-A2 Cyclopropane derivates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-27 EP disclosed
US-4482731-A Process for the preparation of trans-3-(z-2-chloro-2-aryl-vinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid derivatives, and the use of intermediate products in agents for compating pests BAYER AKTIENGESELLSCHAFT (DE) 1984-11-13 US disclosed
US-4440947-A Preparation of substituted alpha-halogeno-propionic acids and their derivatives BAYER AKTIENGESELLSCHAFT (DE) 1984-04-03 US disclosed
US-4435597-A Preparation of caronaldehyde acid and derivatives thereof BAYER AKTIENGESELLSCHAFT (DE) 1984-03-06 US disclosed
US-4206140-A INSECTICIDES, ANTHELMINTICS ROUSSEL UCLAF (FR) 1980-06-03 US disclosed
US-4101574-A Cyclopropanecarboxylic acid chlorides ROUSSEL UCLAF (FR) 1978-07-18 US disclosed