SCHEMBL8037708

SCHEMBL8037708

CC1(C)[C@H](C=O)[C@@H]1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
APLNR P35414 1/20 0.32
UGT2B7 P16662 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515780 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL2692874 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL3247829 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL3216533 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL358648 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL11136789 0.80 LMNA (0.37) LMNA
SCHEMBL7064292 0.80 LMNA (0.37) LMNA
SCHEMBL3678270 0.79 UGT2B7 (0.32) LMNAUGT2B7
SCHEMBL3658221 0.79 UGT2B7 (0.32) LMNAUGT2B7
SCHEMBL11055234 0.79 UGT2B7 (0.32) LMNAUGT2B7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274314-B1 PROCESS FOR THE PREPARATION OF PENTAFLUOROPHENYLMETHYL 2,2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLATE, AND ITS USE IN THE SYNTHESIS OF PESTICIDAL PRODUCTS ROUSSEL-UCLAF (FR) 1990-11-07 EP claimed
EP-0002849-B1 PROCESS FOR THE PREPARATION OF DI-(HALO)-VINYL COMPOUNDS AND DI-(HALO)-VINYL COMPOUNDS PRODUCED THEREBY SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-01-27 EP claimed
EP-0002849-A1 Process for the preparation of di-(halo)-vinyl compounds and di-(halo)-vinyl compounds produced thereby SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-07-11 EP claimed
US-4014918-A Process for the preparation of cyclopropane derivatives and compounds produced therein ROUSSEL-UCLAF (FR) 1977-03-29 US claimed
EP-0842137-B1 A PROCESS FOR THE PREPARATION OF CYCLOPROPANE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR CHEMINOVA AGRO AS (DK) 2000-04-05 EP disclosed
US-5986130-A REACTION OF HYDROXYTETRAHYDROFURANONE AND HALOFLUORINATED ETHANE IN THE PRESENCE OF ZINC CHEMINOVA AGRO A/S (DK) 1999-11-16 US disclosed
EP-0842137-A1 A PROCESS FOR THE PREPARATION OF CYCLOPROPANE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR CHEMINOVA AGRO A/S (DK) 1998-05-20 EP disclosed
WO-1997003941-A1 A PROCESS FOR THE PREPARATION OF CYCLOPROPANE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR CHEMINOVA AGRO A/S (DK) 1997-02-06 WO disclosed
US-5004822-A Isomers of 3-acetyl-2,2-dimethyl cyclopropane carboxylic acid derivatives NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-04-02 US disclosed
US-4622337-A INSECTICIDES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1986-11-11 US disclosed
US-4464391-A Pesticides NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-08-07 US disclosed
US-4014918-A Process for the preparation of cyclopropane derivatives and compounds produced therein ROUSSEL-UCLAF (FR) 1977-03-29 US disclosed