Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17580370 | 0.87 | KDM4E (0.43) | KDM4ECCR2HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL17580899 | 0.84 | PTGDR2 (0.45) | KDM4ECCR2 | |
| SCHEMBL30448661 | 0.83 | HDAC1 (0.43) | KDM4EHSD17B10ALDH1A1CCR2HDAC1 | |
| SCHEMBL3410183 | 0.82 | KMO (0.56) | KDM4EHSD17B10L3MBTL1POLBAPEX1 | |
| SCHEMBL17627894 | 0.81 | TP53 (0.39) | KDM4EALDH1A1MAPTCCR2HDAC1 | |
| SCHEMBL3214955 | 0.81 | KAT2B (0.43) | KDM4EHSD17B10ALDH1A1MAPTMEN1 | |
| SCHEMBL17580830 | 0.80 | PLK1 (0.43) | KDM4EMAPTCCR2HDAC1HDAC6 | |
| SCHEMBL28779597 | 0.80 | HDAC1 (0.43) | KDM4EALDH1A1MAPTHDAC1HDAC6 | |
| SCHEMBL3226989 | 0.80 | ALDH1A1 (0.59) | KDM4EL3MBTL1APEX1ALDH1A1FABP3 | |
| SCHEMBL3222281 | 0.79 | KDM4E (0.47) | KDM4EHSD17B10L3MBTL1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160090383-A1 | ANTIBACTERIAL PHTHALIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2016-03-31 | — | — | US | disclosed |
| EP-2994466-A1 | ANTIBACTERIAL PHTHALIDE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2016-03-16 | — | — | EP | disclosed |
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | NRDC, NACA, NAA50 | KDM4E 3723/4885HSD17B10 3187/4885L3MBTL1 1539/4885 |
| US-20160090383-A1 | ANTIBACTERIAL PHTHALIDE DERIVATIVES | MRPL21, MAPRE1, HDAC6 | KDM4E 1799/4885HSD17B10 1715/4885L3MBTL1 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.