Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210225 | 0.88 | ALDH1A1 (0.43) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL3223002 | 0.80 | MTNR1A (0.52) | — | |
| SCHEMBL3223401 | 0.80 | TAS1R3 (0.41) | ALDH1A1DHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3209462 | 0.75 | PDE10A (0.41) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL3221363 | 0.73 | ALDH1A1 (0.55) | ALDH1A1DHODHHTTMEN1KMT2A | |
| SCHEMBL12049785 | 0.71 | ALDH1A1 (0.55) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL12049791 | 0.70 | ALDH1A1 (0.60) | ALDH1A1DHODHHTTLMNAMEN1 | |
| SCHEMBL3213249 | 0.70 | ALDH1A1 (0.50) | ALDH1A1DHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL12060650 | 0.69 | ALDH1A1 (0.55) | ALDH1A1DHODHTAOK3HTTLMNA | |
| SCHEMBL3210236 | 0.69 | LMNA (0.40) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | claimed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | claimed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | claimed |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | ALDH1A1 128/4885DHODH 1426/4885TAS1R3 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.