Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034389 | 1.00 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL16551739 | 1.00 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL1828151 | 1.00 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL20651084 | 0.83 | TRPM8 (0.45) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL4728415 | 0.83 | TRPM8 (0.54) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL17971599 | 0.80 | — | — | |
| SCHEMBL1603520 | 0.79 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL13033009 | 0.77 | — | — | |
| SCHEMBL13033011 | 0.77 | — | — | |
| SCHEMBL14445027 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318356-B1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | PROCTER & GAMBLE (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2318356-B1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | PROCTER & GAMBLE (US) | 2015-03-11 | — | — | EP | disclosed |
| US-20140186272-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140186272-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140186272-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-8754259-B2 | Synthesis of cyclohexane derivatives useful as sensates in consumer products | THE PROCTER & GAMBLE COMPANY (US) | 2014-06-17 | — | — | US | disclosed |
| US-8754259-B2 | Synthesis of cyclohexane derivatives useful as sensates in consumer products | THE PROCTER & GAMBLE COMPANY (US) | 2014-06-17 | — | — | US | disclosed |
| US-8754259-B2 | Synthesis of cyclohexane derivatives useful as sensates in consumer products | THE PROCTER & GAMBLE COMPANY (US) | 2014-06-17 | — | — | US | disclosed |
| US-20130216486-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130216486-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130216486-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-22 | — | — | US | disclosed |
| US-8426643-B2 | Synthesis of cyclohexane derivatives useful as sensates in consumer products | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426643-B2 | Synthesis of cyclohexane derivatives useful as sensates in consumer products | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426643-B2 | Synthesis of cyclohexane derivatives useful as sensates in consumer products | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120283469-A1 | INTERCONVERSION BETWEEN ISOMERIC P-MENTHANE-3-CARBOXYLIC ACIDS | PINOVA HOLDINGS, INC | 2012-11-08 | — | — | US | disclosed |
| US-20120116113-A1 | PROCESS FOR MAKING NEO-ENRICHED p-MENTHANE COMPOUNDS | RENESSENZ LLC | 2012-05-10 | — | — | US | disclosed |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | THE PROCTER & GAMBLE COMPANY | 2010-03-25 | — | — | US | disclosed |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | THE PROCTER & GAMBLE COMPANY | 2010-03-25 | — | — | US | disclosed |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | THE PROCTER & GAMBLE COMPANY | 2010-03-25 | — | — | US | disclosed |
| WO-2010019730-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140186272-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | NISCH, TRPM4, TRPM8 | TRPM8 3/4885TRPA1 10/4885EPHX1 528/4885 |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | NISCH, TRPM4, TRPM8 | TRPM8 3/4885TRPA1 10/4885EPHX1 528/4885 |
| US-20120283469-A1 | INTERCONVERSION BETWEEN ISOMERIC P-MENTHANE-3-CARBOXYLIC ACIDS | ME1, TASP1, MNS1 | TRPM8 1087/4885TRPA1 781/4885EPHX1 255/4885 |
| US-20120116113-A1 | PROCESS FOR MAKING NEO-ENRICHED p-MENTHANE COMPOUNDS | ME3, MDH2, ME2 | TRPM8 571/4885TRPA1 1863/4885EPHX1 238/4885 |
| US-20130216486-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | NISCH, TRPM4, TRPM8 | TRPM8 3/4885TRPA1 10/4885EPHX1 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.