SCHEMBL1332953

SCHEMBL1332953

CCC(C)OC(=O)C(=Cc1ccc(OC)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.42
TAS1R1 Q7RTX1 2/20 0.42
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
ATM Q13315 1/20 0.41
AKR1C3 P42330 1/20 0.40
GSK3B P49841 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 2/20 0.40
NR1H4 Q96RI1 1/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
MAOB P27338 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11776380 0.87 GLO1 (0.42) TAS1R3TAS1R1LMNAGSK3BALDH1A1
SCHEMBL435678 0.86 KDM4E (0.46) LMNAMEN1KMT2AALDH1A1NR1H4
SCHEMBL3224035 0.86 MEN1 (0.55) LMNAAKR1C3MEN1KMT2AALDH1A1
SCHEMBL11330329 0.86 KDM4E (0.43) LMNANR1H4KDM4E
SCHEMBL1673522 0.85 KMT2A (0.55) TDP1LMNAAKR1C3MEN1KMT2A
SCHEMBL3218589 0.85 MEN1 (0.55) LMNAAKR1C3MEN1KMT2AALDH1A1
SCHEMBL11815879 0.85 GRIK1 (0.42) LMNAAKR1C3MEN1KMT2AALDH1A1
SCHEMBL8737494 0.85 TAS1R3 (0.47) TAS1R3TAS1R1TDP1LMNAGSK3B
SCHEMBL11803682 0.85 THRB (0.44) TAS1R3TAS1R1LMNATHRBMEN1
SCHEMBL11811000 0.85 ALDH1A1 (0.51) LMNAMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4058499-B1 POLYSILOXANE FUNCTIONALIZED POLYURETHANES FOR ENHANCING HYDROPHOBISATION OF SURFACES COVESTRO DEUTSCHLAND AG (DE) 2024-12-04 EP disclosed
EP-4175820-A1 COATINGS FROM POLYISOCYANURATE COATINGS (RIM) AND THEIR USE IN INJECTION MOLDING PROCESSES Covestro Deutschland AG (DE) 2023-05-10 EP disclosed
EP-4058499-A1 POLYSILOXANE-FUNCTIONALIZED POLYURETHANES FOR BOOSTING THE HYDROPHOBICITY OF SURFACES Covestro Intellectual Property GmbH & Co. KG (DE) 2022-09-21 EP disclosed
EP-3994192-A1 RESISTANT 2K-PUR COATINGS Covestro Intellectual Property GmbH & Co. KG (DE) 2022-05-11 EP disclosed
WO-2022002787-A1 COATINGS FROM POLYISOCYANURATE COATINGS (RIM) AND THEIR USE IN INJECTION MOLDING PROCESSES COVESTRO DEUTSCHLAND AG (DE) 2022-01-06 WO disclosed
WO-2021094229-A1 POLYSILOXANE-FUNCTIONALIZED POLYURETHANES FOR BOOSTING THE HYDROPHOBICITY OF SURFACES COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-05-20 WO disclosed
WO-2021001270-A1 RESISTANT 2K-PUR COATINGS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-01-07 WO disclosed
US-9458282-B2 Polyurethane sealing compounds COVESTRO DEUTCHLAND AG (DE) 2016-10-04 US disclosed
US-9458318-B2 Polyisocyanate mixtures COVESTRO DEUTSCHLAND AG (DE) 2016-10-04 US disclosed
US-20130158146-A1 POLYISOCYANATE MIXTURES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-20 US disclosed
US-6262153-B1 Colored wax articles CLARIANT FINANCE (BVI) LIMITED (VG) 2001-07-17 US disclosed
WO-2000022037-A1 SOLID, SHAPED AND COLORED WAX ARTICLES CLARIANT FINANCE (BVI) LIMITED (VG) 2000-04-20 WO disclosed
US-4652493-A POLYURETHANES WITH SUBSTITUTED OXALANILIDES OR INDOLINE DERIVATIVES AS LIGHT PROTECTION AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1987-03-24 US disclosed
US-4263408-A Process for the production of molded foams BAYER AKTIENGESELLSCHAFT (DE) 1981-04-21 US disclosed
US-4189542-A Process for the production of foam moldings having an impervious outer skin using semi-prepolymer prepared from isocyanates such as isophorone diisocyanate BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed
US-4123418-A BIS-(U8I8I8L8L-PENTAMETHY TETRAMETHYL-4-PIPERIDYL)-SUBERATE CIBA-GEIGY CORPORATION (US) 1978-10-31 US disclosed
US-4110304-A STERICALLY HINDERED CYCLIC AMINE CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-4061631-A STABILIZER CIBA-GEIGY CORPORATION (US) 1977-12-06 US disclosed
US-3958003-A HETEROCYCLIC COMPOUND, ANALGESICS CENTRAL NERVOUS SYSTEM DEPRESSANT SANDOZ LTD. (CH) 1976-05-18 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed