Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | PRKDC | P78527 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358033 | 0.86 | ERN1 (0.47) | ERN1ALDH1A1CYP3A4PRKDCMAPT | |
| SCHEMBL29036632 | 0.83 | CYP3A4 (0.49) | ERN1ALDH1A1CYP3A4PRKDCMAPT | |
| SCHEMBL2442735 | 0.81 | CYP1A2 (0.53) | ALDH1A1CYP3A4MAPTHSD17B10CYP1A2 | |
| SCHEMBL23664474 | 0.80 | ALDH1A1 (0.46) | ERN1ALDH1A1CYP3A4MAPTCYP1A2 | |
| SCHEMBL9910897 | 0.79 | CYP3A4 (0.58) | ERN1ALDH1A1CYP3A4PRKDCMAPT | |
| SCHEMBL1808550 | 0.79 | ALDH1A1 (0.49) | ERN1ALDH1A1CYP3A4PRKDCMAPT | |
| SCHEMBL8793429 | 0.79 | CYP1A2 (0.52) | ALDH1A1CYP3A4MAPTHSD17B10CYP1A2 | |
| SCHEMBL21566 | 0.79 | CYP1A2 (0.57) | ALDH1A1CYP3A4MAPTHSD17B10CYP1A2 | |
| SCHEMBL29727863 | 0.79 | CYP1A2 (0.57) | ALDH1A1CYP3A4MAPTHSD17B10CYP1A2 | |
| SCHEMBL2924691 | 0.79 | ERN1 (0.50) | ERN1ALDH1A1CYP3A4PRKDCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721536-B | Phenyl-substituted fused tricyclic compounds and application thereof | 广东东阳光药业有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-109721536-A | The fused tricyclic class compound and application thereof that phenyl replaces | 广东东阳光药业有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-101631461-B | Fluoroalkyl phenylamidines and the purposes as bactericide thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-24 | — | — | CN | disclosed |
| EP-2134170-B1 | FLUORALKYLPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER IP GMBH (DE) | 2015-06-03 | — | — | EP | disclosed |
| US-8299301-B2 | Fluoralkylphenylamidines and the use thereof as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-10-30 | — | — | US | disclosed |
| US-20100093534-A1 | FLUORALKYLPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-04-15 | — | — | US | disclosed |
| US-20100056477-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100056477-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100056477-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| CN-101631461-A | Fluoroalkyl phenylamidines and their use as fungicides | BAYER CROPSCIENCE AG | 2010-01-20 | — | — | CN | disclosed |
| EP-2134170-A1 | FLUORALKYLPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2009-12-23 | — | — | EP | disclosed |
| EP-2088859-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | Bayer CropScience AG (DE) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008110314-A1 | FLUORALKYLPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2008-09-18 | — | — | WO | disclosed |
| EP-1969931-A1 | Fluoroalkyl phenylamidines and their use as fungicides | Bayer CropScience Aktiengesellschaft (DE) | 2008-09-17 | — | — | EP | disclosed |
| WO-2008064780-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008064780-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2008-06-05 | — | — | WO | disclosed |
| EP-0691973-A1 | THIENO-INDOLE DERIVATIVES AS 5HT2c AND 5HT2b ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022871-A1 | THIENO-INDOLE DERIVATIVES AS 5HT2c AND 5HT2b ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093534-A1 | FLUORALKYLPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES | PFAS, DDT, PAH | ERN1 2620/4885ALDH1A1 526/4885CYP3A4 36/4885 |
| US-20100056477-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | NIT2, MLN, ACR | ERN1 3343/4885ALDH1A1 3823/4885CYP3A4 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.