Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.37 |
| ▸ | DHCR24 | Q15392 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14647795 | 0.84 | GPBAR1 (0.48) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 | |
| SCHEMBL3225451 | 0.83 | CDC25A (0.41) | PTPN1GPBAR1EPHA2AKR1B10AKR1B1 | |
| SCHEMBL17825552 | 0.80 | PTPN1 (0.45) | PTPN1GPBAR1EPHA2AKR1B10AKR1B1 | |
| SCHEMBL5406429 | 0.79 | INPP5D (0.47) | PTPN1GPBAR1EPHA2AKR1B10AKR1B1 | |
| SCHEMBL15536784 | 0.76 | VDR (0.48) | INPP5DCDC25ACDC25B | |
| SCHEMBL15536787 | 0.76 | VDR (0.48) | INPP5DCDC25ACDC25B | |
| SCHEMBL6706039 | 0.76 | CDC25A (0.49) | PTPN1GPBAR1EPHA2AKR1B10AKR1B1 | |
| SCHEMBL7417161 | 0.74 | GABRP (0.38) | AKR1B10AKR1B1MEN1LMNAKMT2A | |
| SCHEMBL25711251 | 0.72 | USP2 (0.56) | PTPN1GPBAR1EPHA2AKR1B10AKR1B1 | |
| SCHEMBL9390498 | 0.72 | GPBAR1 (0.38) | PTPN1GPBAR1EPHA2AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010006129-A2 | 2-METHYLENE-(22E)-25-(1-METHYLENE-HEXYL)-26,27-CYCLO-22-DEHYDRO-19-NOR-VITAMIN D ANALOGS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-01-14 | — | — | WO | disclosed |