Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16702992 | 0.84 | CA2 (0.50) | MMP2MMP9MMP8MMP14PTGS2 | |
| SCHEMBL12150079 | 0.81 | TDP1 (0.47) | MMP8POLBMAPTKMT2A | |
| SCHEMBL15993886 | 0.78 | MAPT (0.45) | GAAMAPTKMT2A | |
| SCHEMBL16395052 | 0.78 | GAA (0.61) | MMP2MMP9MMP8MMP14GAA | |
| SCHEMBL2294329 | 0.76 | PTGS2 (0.44) | MMP2MMP9MMP8MMP14PTGS2 | |
| SCHEMBL8613949 | 0.75 | GAA (0.51) | MMP2MMP9MMP8MMP14GAA | |
| SCHEMBL8536427 | 0.73 | MMP8 (0.57) | MMP2MMP9MMP8MMP14GAA | |
| SCHEMBL3235538 | 0.73 | ABCB11 (0.46) | MMP2MMP9MMP8MMP14GAA | |
| SCHEMBL3234259 | 0.73 | MMP2 (0.42) | MMP2MMP9MMP8MMP14PTGS2 | |
| SCHEMBL16703080 | 0.73 | PTGS2 (0.49) | MMP2MMP9MMP8MMP14GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017504-A1 | METHODS OF SYNTHESIZING 1-(ACYLOXY)-ALKYL CARBAMATE PRODRUGS | XENOPORT, INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010017498-A1 | METHODS OF SYNTHESIZING N-HYDROXYSUCCINIMIDYL CARBONATES | XENOPORT, INC. (US) | 2010-02-11 | — | — | WO | disclosed |