SCHEMBL323077

SCHEMBL323077

Nc1ccc(C(F)(C(F)F)C(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.46
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAOB P27338 2/20 0.35
PTGS1 P23219 3/20 0.34
MAPK1 P28482 3/20 0.33
TSHR P16473 3/20 0.33
CYP3A4 P08684 2/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
TP53 P04637 1/20 0.32
PDE2A O00408 1/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8355667 0.89 ALDH1A1 (0.52) KIF11ALDH1A1TDP1MAPTMEN1
SCHEMBL7647444 0.88 ESR1 (0.35) PDE2A
SCHEMBL8496187 0.87 KIF11 (0.43) KIF11ALDH1A1TDP1KDM4EMAPT
SCHEMBL21409916 0.85 KIF11 (0.42) KIF11ALDH1A1TDP1KDM4EMAPT
SCHEMBL10581035 0.79 KCNN4 (0.35) MAPK1CYP3A4RAB9A
SCHEMBL28444481 0.77 TRPV4 (0.31)
SCHEMBL10361813 0.77 MLYCD (0.46) KIF11ALDH1A1TDP1MEN1KMT2A
SCHEMBL3130889 0.77 CYP19A1 (0.39) TDP1MAPTMEN1KMT2AMAPK1
SCHEMBL1719753 0.77 ESR1 (0.54) KIF11ALDH1A1KDM4EMAPTMEN1
SCHEMBL4424761 0.77 ALDH1A1 (0.36) ALDH1A1TDP1KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115723393-B Support body and application thereof 杭州福斯特应用材料股份有限公司 2024-07-16 CN claimed
CN-118344581-A Preparation method of fluorine-rich polyaramid polymer membrane material 南京大学 2024-07-16 CN claimed
CN-118335989-A Positive electrode binder composition and positive electrode 深圳好电科技有限公司 2024-07-12 CN claimed
CN-118290794-A Coating type modified polyimide film with carrier film and preparation method thereof 昆山雅森电子材料科技有限公司 2024-07-05 CN claimed
CN-118271901-A Alcohol-soluble environment-friendly printing ink and preparation method thereof 厦门欧化实业有限公司 2024-07-02 CN claimed
CN-118221936-A High-performance preparation method and application of polyimide 中国科学院化学研究所 2024-06-21 CN claimed
CN-118184603-A Diamine monomer containing piperazine unit, polyimide acid salt separation membrane, and preparation method and application thereof 天津科技大学 2024-06-14 CN claimed
CN-118099359-A Alloy negative electrode material, preparation method thereof, negative electrode material system, negative electrode plate and lithium ion battery 华为技术有限公司 2024-05-28 CN claimed
CN-118092074-A Chemical amplification type positive photosensitive polyimide coating adhesive and preparation method and application thereof 明士(北京)新材料开发有限公司 2024-05-28 CN claimed
CN-118063913-A Composition with good molding property and difficulty in bonding metal, and preparation method and application thereof 上海芯密科技有限公司 2024-05-24 CN claimed
CN-107913580-A A kind of application of polyimides in gas separation 中国科学院长春应用化学研究所 2018-04-17 CN claimed
EP-1368411-A1 PHOTOACTIVE POLYMER Rolic AG (CH) 2003-12-10 EP claimed
WO-2002062873-A9 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-10-03 WO claimed
WO-2002062873-A1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-08-15 WO claimed
US-5780199-A A COPOLYAMIC ACID FROM TETRACARBOXYLIC ACID DIANHYDRIDE, ORGANIC DIAMINE, FLUORINATED DIAMINE, FLUORINATED TETRACARBOXYLIC ACID DIANHYDRIDE, A PHOTOINITIATOR AND SENSITIZER; EXPOSURE TO FORM IMAGES, PATTERNING, CROSSLINKING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-07-14 US claimed
US-5725633-A Sulfonated polyimide gas separation membranes PRAXAIR TECHNOLOGY, INC. (US) 1998-03-10 US claimed
US-5239049-A Selected poly(dianhydrides) compounds, selected poly(amic acid) compounds, and selected poly(imide) compounds OLIN CORPORATION (US) 1993-08-24 US claimed
US-4978738-A FLUORINE-CONTAINING; THIN FILMS HOECHST CELANESE CORP. (US) 1990-12-18 US claimed
EP-0385306-A1 Intermediate molecular weight polyimides and method for their preparation and articles therefrom HOECHST CELANESE CORPORATION (US) 1990-09-05 EP claimed
US-4929405-A Ultrathin polyimide polymer flims and their preparation HOECHST CELANESE CORP. (US) 1990-05-29 US claimed