Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 2/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 8/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229206 | 0.87 | HRH3 (0.53) | HTR7BCL2BAK1ADORA2AADORA1 | |
| SCHEMBL30108234 | 0.82 | HTR7 (0.69) | HTR7ITGB1ITGA4ITGB7ADORA2A | |
| SCHEMBL15826880 | 0.82 | HTR7 (0.69) | HTR7ITGB1ITGA4ITGB7ADORA2A | |
| SCHEMBL2194377 | 0.80 | HTR7 (0.63) | HTR7ITGB1ITGA4ITGB7BCL2 | |
| Hydrochloric Acid SCHEMBL9859525 | 0.79 | HTR7 (0.62) | HTR7ITGB1ITGA4ITGB7BCL2 | |
| SCHEMBL1848899 | 0.78 | NMT1 (0.68) | BCL2 | |
| SCHEMBL8569622 | 0.76 | KDM4E (0.59) | HTR7ITGB1ITGA4ITGB7BCL2 | |
| SCHEMBL3236665 | 0.75 | NMT1 (0.63) | — | |
| SCHEMBL1111854 | 0.75 | PTGS2 (0.49) | HTR7BCL2BAK1 | |
| SCHEMBL27749319 | 0.74 | ACHE (0.47) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828346-B2 | N-myristoyl transferase inhibitors | UNIVERSITY OF DUNDEE (GB) | 2017-11-28 | — | — | US | disclosed |
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |
| US-20160060224-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | UNIVERSITY OF DUNDEE (GB) | 2016-03-03 | — | — | US | disclosed |
| EP-2980076-A1 | PYRAZOLYL DERIVATIVES | University of Dundee (GB) | 2016-02-03 | — | — | EP | disclosed |
| US-9156811-B2 | N-myristoyl transferase inhibitors | Univeristy of Dundee (GB) | 2015-10-13 | — | — | US | disclosed |
| EP-2323987-B1 | N-MYRISTOYL TRANSFERASE INHIBITORS | UNIV DUNDEE (GB) | 2015-06-24 | — | — | EP | disclosed |
| US-20110312921-A1 | N-Myristoyl Transferase Inhibitors | DUNDEE, UNIVERSITY OF (GB) | 2011-12-22 | — | — | US | disclosed |
| WO-2010026365-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | UNIVERSITY OF DUNDEE (GB) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312921-A1 | N-Myristoyl Transferase Inhibitors | GNMT, NNMT, SPTLC1 | HTR7 3601/4885ITGB1 4812/4885ITGA4 4864/4885 |
| US-20160060224-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | GNMT, NNMT, SPTLC1 | HTR7 3601/4885ITGB1 4812/4885ITGA4 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.