Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PYGL | P06737 | 4/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255118 | 0.73 | ALDH1A1 (0.58) | ALDH1A1NPFFR2KMT2ANPSR1CHAT | |
| SCHEMBL3227490 | 0.73 | HSD17B10 (0.46) | AHRHSD17B10 | |
| SCHEMBL10973255 | 0.72 | ALDH1A1 (0.64) | ALDH1A1NPFFR2KMT2ANPSR1CHAT | |
| SCHEMBL10973260 | 0.72 | ALDH1A1 (0.64) | ALDH1A1NPFFR2KMT2ANPSR1CHAT | |
| SCHEMBL3298582 | 0.72 | ALDH1A1 (0.64) | ALDH1A1NPFFR2KMT2ANPSR1CHAT | |
| SCHEMBL10548844 | 0.72 | TTR (0.41) | ALDH1A1KMT2ANPSR1TSHRCYP3A4 | |
| SCHEMBL3218827 | 0.71 | CHRM5 (0.52) | ALDH1A1KMT2ACHATTSHRGAA | |
| SCHEMBL9720852 | 0.70 | CHAT (0.67) | ALDH1A1NPFFR2KMT2ANPSR1CHAT | |
| SCHEMBL9720849 | 0.70 | CHAT (0.67) | ALDH1A1NPFFR2KMT2ANPSR1CHAT | |
| SCHEMBL8580658 | 0.70 | ALDH1A1 (0.61) | ALDH1A1NPFFR2KMT2ANPSR1CHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | CHRM1, PRDX1, CHRM2 | ALDH1A1 1958/4885NPFFR2 327/4885KMT2A 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.