Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600691 | 0.79 | SLC22A6 (0.50) | MAPTTP53HTTKDM4EALDH1A1 | |
| SCHEMBL3925907 | 0.70 | SLC22A6 (0.64) | MAPK1ALDH1A1SLC22A6NR4A2CTNNB1 | |
| SCHEMBL2071022 | 0.69 | ALDH1A1 (0.39) | MAPK1MAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL1401293 | 0.66 | LTA4H (0.41) | MAPTHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3638796 | 0.66 | MAP2 (0.49) | MAPK1MAPTJAK2TP53HTT | |
| SCHEMBL6579403 | 0.66 | KDM4E (0.53) | MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL20239570 | 0.66 | NPSR1 (0.47) | MAPK1MAPTTP53HTTKDM4E | |
| SCHEMBL28404237 | 0.66 | ELANE (0.47) | MAPTTP53KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7883670 | 0.65 | KIF11 (0.39) | MAPK1MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL27790479 | 0.65 | MAPK1 (0.52) | MAPK1MAPTHTTALDH1A1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015636-A1 | BETA-CARBOLIN-DERIVATES AS SUBSTRATES FOR AN ENZYME | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2010-02-11 | — | — | WO | disclosed |