SCHEMBL3236452

SCHEMBL3236452

C=CC(=O)NCc1ncc[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.50
TAAR1 Q96RJ0 1/20 0.42
TGM2 P21980 1/20 0.42
TBXAS1 P24557 2/20 0.41
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KLK1 P06870 1/20 0.38
KLK5 Q9Y337 1/20 0.38
FDPS P14324 1/20 0.38
NTRK1 P04629 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA2B P29275 1/20 0.38
ADORA1 P30542 1/20 0.38
ROCK2 O75116 1/20 0.37
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TERT O14746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7198930 0.84 TERT (0.49) FPR2TBXAS1MAPK1ALDH1A1TSHR
SCHEMBL435392 0.81 TBXAS1 (0.50) TBXAS1GAATERT
SCHEMBL5630310 0.81 FPR2 (0.54) FPR2TAAR1TBXAS1MAPK1KLK1
SCHEMBL27993527 0.80 TBXAS1 (0.52) TGM2TBXAS1GAATERT
SCHEMBL6451096 0.79 FPR2 (0.55) FPR2TAAR1TBXAS1MAPK1KLK1
SCHEMBL4141453 0.78 FPR2 (0.51) FPR2TAAR1TBXAS1MAPK1KLK1
SCHEMBL5630316 0.77 FPR2 (0.54) FPR2TAAR1TBXAS1MAPK1KLK1
SCHEMBL14612333 0.77 FPR2 (0.54) FPR2TAAR1TBXAS1MAPK1KLK1
SCHEMBL1258259 0.77 FPR2 (0.54) FPR2TAAR1TBXAS1MAPK1KLK1
SCHEMBL6029787 0.75 FPR2 (0.51) FPR2TAAR1TBXAS1MAPK1KLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2328547-B1 COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS BASF SE (DE) 2014-03-05 EP claimed
EP-2039343-B1 Cosmetic compositions containing a cationic copolymer and a particular amino silicone and uses thereof OREAL (FR) 2012-12-05 EP claimed
EP-2072084-A2 Cosmetic compositions containing a cationic copolymer, an amino silicone and a cationic polymer, and uses thereof L'Oréal (FR) 2009-06-24 EP claimed
US-20090130038-A1 COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE CATIONIC POLYMER AND AT LEAST ONE ESTER OF A C8-C24 FATTY ACID AND OXYETHYLENATED SORBITAN COMPRISING 2 TO 10 OXYETHYLENE MOTIFS, AND COSMETIC TREATMENT METHODS EMPLOYING SAID COMPOSITIONS L'OREAL S.A. (FR) 2009-05-21 US claimed
EP-2039344-A2 Cosmetic composition comprising a cationic copolymer and an anionic associative polymer and cosmetic treatment process L'Oréal (FR) 2009-03-25 EP claimed
EP-2039345-A1 Cosmetic compositions containing a cationic copolymer and a particular triglyceride and uses thereof L'Oréal (FR) 2009-03-25 EP claimed
EP-2039346-A1 Cosmetic composition comprising a cationic copolymer and a starch and cosmetic treatment process L'Oréal (FR) 2009-03-25 EP claimed
EP-2039343-A1 Cosmetic compositions containing a cationic copolymer and a particular amino silicone and uses thereof L'Oréal (FR) 2009-03-25 EP claimed
US-20090074696-A1 COSMETIC COMPOSITION COMPRISING A CATIONIC COPOLYMER AND A STARCH AND COSMETIC TREATMENT PROCESS THEREOF L'OREAL S.A. (FR) 2009-03-19 US claimed
EP-2036590-A2 Cosmetic compositions containing a cationic copolymer, a cyclodextrin and a surfactant, and uses thereof L'Oréal (FR) 2009-03-18 EP claimed
EP-0707077-B1 Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same ORTHO CLINICAL DIAGNOSTICS INC (US) 2004-11-17 EP claimed
EP-0702006-B1 Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLIN DIAG (US) 2000-05-10 EP claimed
US-5582988-A PRECIPITAION OF NUCLEIC ACID AND CATION POLYMER AT ACIDIC PH; ADJUSTMENT OF PH TO RELEASE NUCLEIC ACID JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-12-10 US claimed
US-5523368-A Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-06-04 US claimed
EP-0707077-A2 Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-04-17 EP claimed
EP-0702006-A1 Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-03-20 EP claimed
US-8846017-B2 Cosmetic compositions comprising at least one cationic copolymer and at least one amino silicone and methods of use thereof L'OREAL (FR) 2014-09-30 US disclosed
EP-2039343-B1 Cosmetic compositions containing a cationic copolymer and a particular amino silicone and uses thereof OREAL (FR) 2012-12-05 EP disclosed
EP-0702006-A1 Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-03-20 EP disclosed
US-5434270-A Weakly basic polymerizable monomers and polymers prepared therefrom EASTMAN KODAK COMPANY (US) 1995-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074696-A1 COSMETIC COMPOSITION COMPRISING A CATIONIC COPOLYMER AND A STARCH AND COSMETIC TREATMENT PROCESS THEREOF TYR, OXGR1, OGFOD1 FPR2 2096/4885TAAR1 432/4885TGM2 1548/4885
US-20090130038-A1 COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE CATIONIC POLYMER AND AT LEAST ONE ESTER OF A C8-C24 FATTY ACID AND OXYETHYLENATED SORBITAN COMPRISING 2 TO 10 OXYETHYLENE MOTIFS, AND COSMETIC TREATMENT METHODS EMPLOYING SAID COMPOSITIONS FABP4, FFAR4, ANXA4 FPR2 550/4885TAAR1 2042/4885TGM2 2550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.