SCHEMBL435392

SCHEMBL435392

C=CC(=O)NCCCc1ncc[nH]1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.50
NAMPT P43490 12/20 0.44
TERT O14746 1/20 0.43
GAA P10253 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
PBK Q96KB5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27993527 0.96 TBXAS1 (0.52) TBXAS1NAMPTTERTGAAZDHHC20
SCHEMBL7198930 0.91 TERT (0.49) TBXAS1NAMPTTERTGAAZDHHC20
SCHEMBL4373409 0.82 FPR2 (0.37) TBXAS1NAMPTGAAPBK
SCHEMBL3236452 0.81 FPR2 (0.50) TBXAS1TERTGAA
SCHEMBL2780861 0.80 TBXAS1 (0.54) TBXAS1NAMPTTERTPBK
SCHEMBL935332 0.79 TBXAS1 (0.50) TBXAS1NAMPTTERTPBK
SCHEMBL5142038 0.79 TBXAS1 (0.53) TBXAS1NAMPTTERTPBK
Hydrochloric Acid SCHEMBL8108651 0.78 TBXAS1 (0.51) TBXAS1NAMPTTERTPBK
SCHEMBL6314871 0.78 ZDHHC20 (0.41) TBXAS1GAAZDHHC20ZDHHC2
SCHEMBL7297042 0.78 TBXAS1 (0.51) TBXAS1NAMPTTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582684-B2 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-01 US claimed
EP-0707077-B1 Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same ORTHO CLINICAL DIAGNOSTICS INC (US) 2004-11-17 EP claimed
US-5582988-A PRECIPITAION OF NUCLEIC ACID AND CATION POLYMER AT ACIDIC PH; ADJUSTMENT OF PH TO RELEASE NUCLEIC ACID JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-12-10 US claimed
US-5523368-A Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-06-04 US claimed
EP-0707077-A2 Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-04-17 EP claimed
EP-0702006-A1 Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-03-20 EP claimed
US-12630582-B2 Method for biomaterial purification and kits thereof Life Technologies Corporation (US) 2026-05-19 US disclosed
US-20250367610-A1 Block Copolymers Grafted to Porous Polymeric Substrate SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-12-04 US disclosed
EP-4543575-A1 BLOCK COPOLYMERS GRAFTED TO POROUS POLYMERIC SUBSTRATE Solventum Intellectual Properties Company (US) 2025-04-30 EP disclosed
EP-2588219-B1 FILTER PLATE ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY NEOGEN FOOD SAFETY US HOLDCO CORP (US) 2024-05-29 EP disclosed
US-20240059731-A1 Method for Biomaterial Purification and Kits Thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-02-22 US disclosed
US-20240010674-A1 A FILTRATION UNIT AND A METHOD FOR BIOMATERIAL PURIFICATION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-01-11 US disclosed
WO-2023248020-A1 BLOCK COPOLYMERS GRAFTED TO POROUS POLYMERIC SUBSTRATE 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-28 WO disclosed
US-5523368-A Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-06-04 US disclosed
EP-0707077-A2 Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-04-17 EP disclosed
EP-0702006-A1 Weakly basic polymerizable monomers and polymers prepared therefrom JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-03-20 EP disclosed
EP-0699072-A1 IRON-BINDING POLYMERS FOR ORAL ADMINISTRATION GELTEX PHARMACEUTICALS, INC. (US) 1996-03-06 EP disclosed
US-5487888-A Iron-binding polymers for oral administration GELTEX, INC. (US) 1996-01-30 US disclosed
US-5434270-A Weakly basic polymerizable monomers and polymers prepared therefrom EASTMAN KODAK COMPANY (US) 1995-07-18 US disclosed
WO-1994027621-A1 IRON-BINDING POLYMERS FOR ORAL ADMINISTRATION GELTEX, INC. (US) 1994-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059731-A1 Method for Biomaterial Purification and Kits Thereof BMP2, ADM2, PLOD3 TBXAS1 2459/4885NAMPT 3388/4885TERT 1545/4885
US-12630582-B2 Method for biomaterial purification and kits thereof CD68, FIBP, BMP2 TBXAS1 3108/4885NAMPT 3608/4885TERT 834/4885
US-20240010674-A1 A FILTRATION UNIT AND A METHOD FOR BIOMATERIAL PURIFICATION CD68, PLAUR, BMP2 TBXAS1 4346/4885NAMPT 4399/4885TERT 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.