SCHEMBL3239072

SCHEMBL3239072

CC(C)=CCc1cc2c(cc1O)oc(=O)c1c3ccc(O)cc3oc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5AP P20292 1/20 1.00
▸ KDM4E B2RXH2 3/20 0.60
▸ MEN1 O00255 3/20 0.60
▸ MAPT P10636 3/20 0.60
▸ KMT2A Q03164 3/20 0.60
▸ GAA P10253 3/20 0.60
▸ ESR1 P03372 2/20 0.60
▸ ESR2 Q92731 2/20 0.60
▸ MGAM O43451 2/20 0.60
▸ HPGD P15428 2/20 0.60
▸ RECQL P46063 2/20 0.60
▸ BLM P54132 2/20 0.60
▸ MAOA P21397 2/20 0.60
▸ NR1I2 O75469 1/20 0.60
▸ ALDH1A1 P00352 1/20 0.60
▸ LMNA P02545 1/20 0.60
▸ GLA P06280 1/20 0.60
▸ POLB P06746 1/20 0.60
▸ THRB P10828 1/20 0.60
▸ CSNK2A2 P19784 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30637432 0.91 ALOX5AP (0.83) ALOX5APKDM4EMEN1MAPTKMT2A
SCHEMBL26621109 0.90 ALOX5AP (0.82) ALOX5APKDM4EMEN1MAPTKMT2A
SCHEMBL30005641 0.89 ALOX5AP (0.80) ALOX5APKDM4EMEN1MAPTKMT2A
SCHEMBL32676365 0.84 ALOX5AP (0.72) ALOX5APKDM4EMEN1MAPTKMT2A
SCHEMBL29497159 0.82 ALOX5AP (0.69) ALOX5APKDM4EMEN1MAPTKMT2A
SCHEMBL15383650 0.82 ALOX5AP (0.69) ALOX5APKDM4EMEN1MAPTKMT2A
Glycyrol SCHEMBL758197 0.79 ALOX5AP (0.65) ALOX5APKDM4EMEN1MAPTKMT2A
Glycyrol SCHEMBL29499208 0.79 ALOX5AP (0.65) ALOX5APKDM4EMEN1MAPTKMT2A
Coumestrol SCHEMBL22012 0.77 ESR2 (1.00) ALOX5APKDM4EMEN1MAPTKMT2A
Coumestrol SCHEMBL29453366 0.77 ESR2 (1.00) ALOX5APKDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720261-A1 NOVEL CULTURE CONDITIONS FOR CLONAL EXPANSION OF NEPHRON PROGENITOR CELLS, GENERATION OF NEPHRON ORGANOIDS, AND RAPID AND SCALABLE MODELING OF POLYCYSTIC KIDNEY DISEASE University of Southern California (US) 2026-04-08 — — EP claimed
US-20260041097-A1 PLANT PRIMING COMPOSITIONS AND METHODS OF USE THEREOF ZERO GRAVITY SOLUTIONS INC (US) 2026-02-12 — — US claimed
US-20250332143-A1 COMPOSITION COMPRISING ALOX5 INHIBITOR FOR PREVENTING OR TREATING SARCOPENIA PLUTO INC (KR) 2025-10-30 — — US claimed
US-20250213585-A1 COMPOSITIONS AND METHODS OF A CONCOMITANT THERAPY OF ALTERNATING ELECTRIC FIELDS AND NOTCH-1 INHIBITOR SHANGHAI INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY (CN) 2025-07-03 — — US claimed
EP-4494639-A1 COMPOSITION COMPRISING ALOX5 INHIBITOR FOR PREVENTING OR TREATING SARCOPENIA Pluto Inc. (KR) 2025-01-22 — — EP claimed
WO-2024243567-A1 NOVEL CULTURE CONDITIONS FOR CLONAL EXPANSION OF NEPHRON PROGENITOR CELLS, GENERATION OF NEPHRON ORGANOIDS, AND RAPID AND SCALABLE MODELING OF POLYCYSTIC KIDNEY DISEASE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-11-28 — — WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 — — WO claimed
WO-2023177128-A1 COMPOSITION COMPRISING ALOX5 INHIBITOR FOR PREVENTING OR TREATING SARCOPENIA 주식회사 플루토 2023-09-21 — — WO claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US claimed
US-9661857-B2 Compositions for controlling plant parasitic nematodes YAMASHITA THOMAS T (US) 2017-05-30 — — US claimed
WO-2015081199-A1 COMPOSITIONS AND METHODS FOR TREATING HERPESVIRUS INFECTION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2015-06-04 — — WO claimed
US-8367121-B2 Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease FLORIDA A & M UNIVERSITY (US) 2013-02-05 — — US claimed
CN-101213980-B Biological pesticide using psoralidin to prevent and control plant fungal diseases SHENYANG INST OF CHEMICAL TECH 2011-05-18 — — CN claimed
US-20100150895-A1 Nutraceutical agent for attenuating the Neurodegenerative process associated with Parkinson's disease NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-06-17 — — US claimed
US-20080292607-A1 Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease MAZZIO ELIZABETH 2008-11-27 — — US claimed
CN-101213980-A Biological pesticide using psoralidin to prevent and control plant fungal diseases SHENYANG INST OF CHEMICAL TECH (CN) 2008-07-09 — — CN claimed
US-20070116779-A1 Comprehensive nutraceutical agent for treatment/ prevention of Parkinson's disease MAZZIO ELIZABETH 2007-05-24 — — US claimed
WO-2001001996-A9 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS UNIV WESTERN AUSTRALIA (AU) 2002-09-12 — — WO claimed
WO-2001001996-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS UNIVERSITY OF WESTERN AUSTRALIA (AU) 2001-01-11 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB ALOX5AP 1616/4885KDM4E 4637/4885MEN1 1711/4885
US-20250332143-A1 COMPOSITION COMPRISING ALOX5 INHIBITOR FOR PREVENTING OR TREATING SARCOPENIA MYOF, ALOX5, MYLK2 ALOX5AP 6/4885KDM4E 636/4885MEN1 4605/4885
US-20260041097-A1 PLANT PRIMING COMPOSITIONS AND METHODS OF USE THEREOF XBP1, TFEB, AOC1 ALOX5AP 2670/4885KDM4E 307/4885MEN1 4754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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