Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15184721 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL2690940 | 0.83 | CYP2C9 (0.43) | ALDH1A1CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL8652049 | 0.81 | CYP2C9 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL23456217 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL7192197 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A | |
| SCHEMBL10683688 | 0.79 | CYP2C19 (0.50) | ALDH1A1CYP2C9CYP2C19CYP1A2ACP3 | |
| SCHEMBL29435914 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL28707980 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL2894539 | 0.77 | CYP2C19 (0.52) | ALDH1A1CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL1527192 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CYP2C9CYP2C19CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937091-B2 | Inhibitor of protein crosslinking and use of the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-01-20 | — | — | US | disclosed |
| US-20140031562-A1 | Method for Forming Allylic Alcohols | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031562-A1 | Method for Forming Allylic Alcohols | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031562-A1 | Method for Forming Allylic Alcohols | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) | 2014-01-30 | — | — | US | disclosed |
| US-20120277423-A1 | PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY | 2012-11-01 | — | — | US | disclosed |
| US-8138377-B2 | Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use | DOV PHARMACEUTICAL, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| WO-2010025366-A2 | METHOD FOR FORMING ALLYLIC ALCOHOLS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010025366-A2 | METHOD FOR FORMING ALLYLIC ALCOHOLS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-03-04 | — | — | WO | disclosed |
| US-20080293822-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | ETHISMOS RESEARCH, INC. | 2008-11-27 | — | — | US | disclosed |
| US-20080269348-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | ETHISMOS RESEARCH, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080194696-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | ETHISMOS RESEARCH, INC. | 2008-08-14 | — | — | US | disclosed |
| EP-0647596-B1 | Method of treating water by using 5-allyldibenzosuberenol | KURITA WATER IND LTD (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-5635575-A | POLYMER INCORPORATING UNITS OF LABELED MONOMER WHICH IS LABELED WITH A FLUORESCENT SUBSTANCE AND HAS AN ALLYL GROUP | KURITA WATER INDUSTRIES LTD. (JP) | 1997-06-03 | — | — | US | disclosed |
| US-5624995-A | POLYMER CONTAINING FLUORESCENT COMPOUND WITH AN ALLYL GROUP, EASY ADJUSTMENT OF CONCENTRATION | KURITA WATER INDUSTRIES LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0647596-A2 | A polymer containing agent for water treatment and process for producing said polymer | Kurita Water Industries Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |
| US-4782169-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194696-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | HTR2C, HTR1B, HTR3C | ALDH1A1 379/4885CYP2C9 208/4885CYP2C19 180/4885 |
| US-20140031562-A1 | Method for Forming Allylic Alcohols | ADH1A, ADH1C, ADH5 | ALDH1A1 21/4885CYP2C9 169/4885CYP2C19 422/4885 |
| US-20080293822-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | HTR2C, HTR1B, HTR3C | ALDH1A1 379/4885CYP2C9 208/4885CYP2C19 180/4885 |
| US-20080269348-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | HTR2C, HTR1B, HTR3C | ALDH1A1 379/4885CYP2C9 208/4885CYP2C19 180/4885 |
| US-20120277423-A1 | PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME | ARGLU1, F12, CDKL1 | ALDH1A1 2990/4885CYP2C9 1655/4885CYP2C19 2032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.