Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652062 | 1.00 | KMT2A (0.49) | KMT2ACYP2C19MEN1KDM4ECYP1A2 | |
| SCHEMBL15142922 | 0.87 | PKM (0.51) | KMT2ACYP2C19MEN1KDM4ECYP1A2 | |
| SCHEMBL5194675 | 0.86 | P2RX7 (0.52) | KMT2ACYP2C19MEN1KDM4ECYP1A2 | |
| SCHEMBL38652446 | 0.85 | MTNR1A (0.45) | KMT2ACYP2C19MEN1CYP1A2MTNR1A | |
| SCHEMBL29643774 | 0.85 | PTK2 (0.49) | KMT2AKDM4EATMMTNR1ADAO | |
| SCHEMBL9278020 | 0.85 | TP53 (0.45) | KMT2ACYP2C19MEN1KDM4ECYP1A2 | |
| SCHEMBL38652459 | 0.85 | HTT (0.56) | KDM4EMTNR1AHTR6L3MBTL1LMNA | |
| SCHEMBL30167862 | 0.84 | CYP2C19 (0.53) | KMT2ACYP2C19MEN1MTNR1AP2RX7 | |
| Ethoxycarbonyl Group SCHEMBL27728898 | 0.84 | MTNR1A (0.43) | KMT2ACYP2C19MEN1KDM4ECYP1A2 | |
| SCHEMBL38652180 | 0.82 | KDM4E (0.56) | KMT2ACYP2C19MEN1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471044-B | Synthesis method of palladium-catalyzed 3-aryl 7-azaindole compound | 西北大学 | 2021-08-10 | — | — | CN | claimed |
| CN-111471044-A | Synthesis method of palladium-catalyzed 3-aryl 7-azaindole compound | 西北大学 | 2020-07-31 | — | — | CN | claimed |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | disclosed |
| CN-111253424-B | Silylation of aromatic heterocycles over earth-rich transition metal-free catalysts | 加州理工学院 | 2023-06-20 | — | — | CN | disclosed |
| EP-3705482-B1 | SILYLATION OF AROMATIC HETEROCYCLES BY EARTH ABUNDANT TRANSITION-METAL-FREE CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2023-02-22 | — | — | EP | disclosed |
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2022-12-13 | — | — | US | disclosed |
| US-20220185828-A1 | Silylated Derivatives Of Aromatic Heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-06-16 | — | — | US | disclosed |
| US-20220185828-A1 | Silylated Derivatives Of Aromatic Heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-06-16 | — | — | US | disclosed |
| US-11312733-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-04-26 | — | — | US | disclosed |
| CN-1649889-A | Process for preparing oligonucleotides | AVECIA LTD (GB) | 2005-08-03 | — | — | CN | disclosed |
| EP-1554300-A1 | PHOSPHITYLATION PROCESS | Avecia Biotechnology, Inc. (US) | 2005-07-20 | — | — | EP | disclosed |
| EP-1501851-A1 | PROCESS FOR PREPARING OLIGONUCLEOTIDES | Avecia Limited (GB) | 2005-02-02 | — | — | EP | disclosed |
| CN-1549820-A | Activators for oligonucleotide synthesis | ƽ | 2004-11-24 | — | — | CN | disclosed |
| WO-2004055036-A1 | PROCESS FOR THE PREPARATION OF OLIGONUCLEOTIDES | AVECIA LIMITED (GB) | 2004-07-01 | — | — | WO | disclosed |
| WO-2004035599-A1 | PHOSPHITYLATION PROCESS | AVECIA BIOTECHNOLOGY INC. (US) | 2004-04-29 | — | — | WO | disclosed |
| EP-1404696-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | Avecia Biotechnology, Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003091267-A1 | PROCESS FOR PREPARING OLIGONUCLEOTIDES | AVECIA LIMITED (GB) | 2003-11-06 | — | — | WO | disclosed |
| WO-2003004512-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | AVECIA BIOTECHNOLOGY INC. (US) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312733-B2 | Silylated derivatives of aromatic heterocycles | KCNH1, KCNH3, HNRNPH3 | KMT2A 654/4885CYP2C19 2437/4885MEN1 3045/4885 |
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | USP28, USP25, USP24 | KMT2A 339/4885CYP2C19 2677/4885MEN1 3554/4885 |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | KCNH1, KCNH3, HNRNPH3 | KMT2A 654/4885CYP2C19 2437/4885MEN1 3045/4885 |
| US-20220185828-A1 | Silylated Derivatives Of Aromatic Heterocycles | KCNH1, KCNH3, HNRNPH3 | KMT2A 654/4885CYP2C19 2437/4885MEN1 3045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.