Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238795 | 0.82 | GSK3B (0.53) | ALDH1A1KDM4EKMT2AGSK3BTYMP | |
| SCHEMBL19731398 | 0.72 | TYMP (0.64) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL3127877 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL30954248 | 0.68 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL5652631 | 0.67 | PARP1 (0.48) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| SCHEMBL13738861 | 0.67 | PARP1 (0.61) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL30577482 | 0.67 | PARP1 (0.61) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL4146416 | 0.66 | PDE3B (0.44) | ALDH1A1KDM4EKMT2APARP1TP53 | |
| SCHEMBL4487862 | 0.66 | KIF11 (0.58) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL30577754 | 0.66 | METAP2 (0.49) | ALDH1A1KDM4EKMT2AGSK3BPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036123-A1 | PROCESS FOR THE PREPARATION OF 2,4-DICHLORO-7H-PYRROLO[2,3H]QUINAZOLINE | WYETH (US) | 2010-02-11 | — | — | US | claimed |
| US-20100036123-A1 | PROCESS FOR THE PREPARATION OF 2,4-DICHLORO-7H-PYRROLO[2,3H]QUINAZOLINE | WYETH (US) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036123-A1 | PROCESS FOR THE PREPARATION OF 2,4-DICHLORO-7H-PYRROLO[2,3H]QUINAZOLINE | NQO2, QDPR, DHPS | ALDH1A1 1113/4885KDM4E 1260/4885KMT2A 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.